Vaikutyte-Ramanauskiene Roberta, Puslys Tautvydas, Pukenyte Evelina, Mickiene Aukse
Department of Infectious Diseases, Lithuanian University of Health Sciences Kaunas Hospital, Baltijos str. 120, Kaunas LT-47144, Lithuania.
Department of Neurology, Lithuanian University of Health Sciences, Eivenių str. 2, Kaunas LT-50161, Lithuania.
IDCases. 2024 Aug 2;37:e02050. doi: 10.1016/j.idcr.2024.e02050. eCollection 2024.
Streptococcus suis is an emerging zoonotic pathogen that can cause infections in pigs and humans, usually after ingestion of raw pork meat or wound contamination. We report the first S. suis meningitis and sepsis case in a human in Lithuania. 51 y.o. man with no relevant comorbidities, but with a history of alcohol abuse was admitted to the emergency department due to new-onset tonic-clonic seizures. The patient became agitated, aggressive and hypotensive, later sensible contact was lost (GCS of 8 points). Blood tests and cerebrospinal fluid (CSF) analysis were consistent with bacterial meningitis, thus ceftriaxone and ampicillin were empirically started. S. suis, susceptible to penicillin and ceftriaxone, was identified in blood and CSF cultures. The patient recovered without any immediate significant sequels, but later developed cognitive impairment. The route of infection for our patient was not clear because he had no contact with pigs or raw pork, although he lived in the countryside, helped farmers with non-pig related work, had some scabs on his shins and ate home-cooked pork. The paper presents the case report and review of the literature.
猪链球菌是一种新出现的人畜共患病原体，通常在摄入生猪肉或伤口受污染后可导致猪和人类感染。我们报告了立陶宛首例人类感染猪链球菌引起的脑膜炎和败血症病例。一名51岁男性，无相关合并症，但有酗酒史，因新发强直阵挛性癫痫发作被收入急诊科。患者变得烦躁、好斗且血压降低，随后失去意识（格拉斯哥昏迷评分8分）。血液检查和脑脊液分析结果与细菌性脑膜炎相符，因此经验性地开始使用头孢曲松和氨苄西林治疗。在血液和脑脊液培养物中鉴定出对青霉素和头孢曲松敏感的猪链球菌。患者康复，未出现任何即刻的严重后遗症，但后来出现了认知障碍。该患者的感染途径尚不清楚，因为他虽生活在农村，帮助农民做与猪无关的工作，小腿有一些结痂，且食用自家烹饪的猪肉，但并未接触过猪或生猪肉。本文呈现了该病例报告及文献综述。
