Department of Biological Sciences, School of Basic Sciences, The Libyan Academy of Graduate Studies, Tripoli, Libya.
Department of Medical Lab Technology Science, University of Wadi-Al-Shatii, Brak, Libya.
Pan Afr Med J. 2024 May 28;48:23. doi: 10.11604/pamj.2024.48.23.38566. eCollection 2024.
brucellosis is a global neglected zoonotic disease affecting mainly livestock, causing communicable and zoonotic infections. This study aimed to investigate the seroprevalence and determine epidemiological risk factors associated with Brucella infection in sheep and goats in Al Jufrah central district of Libya.
sera samples from 555 animals (goats (n=320) and sheep (n=235)) sheep) were obtained and subjected to the Rose Bengal Plate Test (RBPT) then further confirmed by a validated Enzyme Linked Immunosorbent assay (ELISA). Collected data was analyzed using Statistical Package for the Social Sciences (SPSS).
in total, 2.7% were ELISA seropositive for brucellosis with the highest seropositivity rate among the studied animals from Sokna with 5.8% (n=13/225) followed by 0.7% (n=2/285) in Waddan and 0% (n=0/45) in Houn. Only location was identified as a significant risk and no significant differences were identified between seropositivity and the age studied groups, species of animals, gender, and size of farms (p-value>0.05).
the present study provides important information on the epidemiological status of Brucella infection in an important region in North Africa. Prevention control systems adopting "One Health" concept, and regional and international collaboration are important to control brucellosis and other zoonotic and transboundary diseases.
布鲁氏菌病是一种全球性被忽视的动物传染病，主要影响牲畜，可引起传染性和动物传染病。本研究旨在调查利比亚朱夫拉中心区绵羊和山羊中布鲁氏菌感染的血清流行率，并确定与布鲁氏菌感染相关的流行病学危险因素。
采集了 555 份动物血清样本（山羊（n=320）和绵羊（n=235）），并进行了虎红平板试验（RBPT），然后用经过验证的酶联免疫吸附试验（ELISA）进一步确认。使用社会科学统计软件包（SPSS）分析收集的数据。
共有 2.7%的动物 ELISA 血清呈布鲁氏菌阳性，其中 Sokna 地区的阳性率最高，为 5.8%（n=13/225），其次是 Waddan 的 0.7%（n=2/285）和 Houn 的 0%（n=0/45）。只有地理位置被确定为一个显著的危险因素，而在研究的年龄组、动物种类、性别和农场规模之间，没有发现血清阳性率的显著差异（p 值>0.05）。
本研究提供了关于北非一个重要地区布鲁氏菌感染的流行病学现状的重要信息。采用“同一健康”概念的预防控制系统以及区域和国际合作，对于控制布鲁氏菌病和其他动物传染病和跨界疾病非常重要。
