Uncovering the Absolute Structure of the Malarial Pigment Crystal, Hemozoin, Using Cryo-electron Tomography and Three-Dimensional Electron Diffraction.
作者信息
Sutanto Renaldo, Mosalaganti Shyamal
机构信息
Life Science Institute, University of Michigan, Ann Arbor, Michigan 48109, United States.
Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109, United States.
出版信息
ACS Cent Sci. 2024 Aug 15;10(8):1439-1441. doi: 10.1021/acscentsci.4c01267. eCollection 2024 Aug 28.
Abstract
摘要
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Uncovering the Absolute Structure of the Malarial Pigment Crystal, Hemozoin, Using Cryo-electron Tomography and Three-Dimensional Electron Diffraction.利用冷冻电子断层扫描和三维电子衍射揭示疟色素晶体（疟原虫血色素）的绝对结构
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本文引用的文献
1
Identification of essential histidine residues involved in heme binding and Hemozoin formation in heme detoxification protein from Plasmodium falciparum.鉴定恶性疟原虫血红素解毒蛋白中参与血红素结合和疟色素形成的必需组氨酸残基。
Sci Rep. 2014 Aug 20;4:6137. doi: 10.1038/srep06137.
2
Heme-binding properties of heme detoxification protein from Plasmodium falciparum.恶性疟原虫血红素解毒蛋白的血红素结合特性。
Biochem Biophys Res Commun. 2013 Oct 4;439(4):477-80. doi: 10.1016/j.bbrc.2013.08.100. Epub 2013 Sep 8.
3
Antimalarial drugs inhibiting hemozoin (beta-hematin) formation: a mechanistic update.抑制疟原虫血红素（β-血红素）形成的抗疟药物：机制更新
Life Sci. 2007 Feb 6;80(9):813-28. doi: 10.1016/j.lfs.2006.11.008. Epub 2006 Nov 10.
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