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使用BRANT-MERQS评分表对类风湿关节炎患者和2型糖尿病患者的3类药物评估质量进行评估。

Use of the BRANT-MERQS scoring table for the quality assessment of type 3 medication review in patients with rheumatoid arthritis and those with type 2 diabetes mellitus.

作者信息

Robberechts Anneleen, Stas Kaat, Puttemans Margot, Poppe Laura, Steurbaut Stephane, De Meyer Guido R Y, De Loof Hans

机构信息

Meduplace, Royal Pharmacists Association of Antwerp (KAVA), Antwerp, Belgium.

Laboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium.

出版信息

Front Pharmacol. 2024 Aug 16;15:1359568. doi: 10.3389/fphar.2024.1359568. eCollection 2024.

Abstract

BACKGROUND

A type 3 medication review (MR3) is a patient-centred medication service primarily provided by pharmacists and is presently employed routinely in several countries. In this process, pharmacists interview patients and collaborate with the treating physician to optimize the patient's pharmacotherapy, taking into account the patient's medication history and other medical data including laboratory values. The need to maintain the quality of such interventions during and after their initial implementation cannot be overstated.

AIM

The objective of this study was to refine and assess a scoring table to evaluate the quality of MR3 conducted in Belgian community pharmacies.

METHODS

The comprehensive quality of MR3s was assessed by scoring its various components using a previously developed scoring table, called BRANT-MERQS, Brussels Antwerp Medication Review Quality Score. MR3s were analysed from an implementation study with patients suffering from rheumatoid arthritis (RA, subproject 1) and type 2 diabetes mellitus (T2DM, subproject 2). Additional information was obtained during a telephone call with a subset of participating pharmacists of subproject 1 who finalized their first MR3.

RESULTS

In subproject 1, a total of 21 MR3s of patients with RA were examined. The assessment showed favourable scores for elements such as a well-organized medication schedule, treatment adherence, and the elaboration of specific interventions. However, certain other quality criteria posed challenges in the evaluation, for example, the use of simple and understandable language. Pharmacists faced time constraints, and elderly general practitioners (GPs) displayed limited enthusiasm, which were notable barriers observed for this subproject. In the context of subproject 2 that investigated 41 MR3s in patients with T2DM, the quality criteria of interaction between pharmacist and GP, and used sources and tools received high scores. However, there was still room for improvement, especially in areas such as accurate dosing, handling kidney function, QT prolongation, correctly associating laboratory values with relevant drugs and medical conditions, and optimisation of medication schedules for patients.

CONCLUSION

This study demonstrated the feasibility of MR3 quality assessment through a scoring system. However, it also unveiled the tool's current imperfections and highlighted the ongoing need for refinement, something expected of a new service in an implementation phase.

摘要

背景

3型药物审查(MR3)是一项以患者为中心的药物服务,主要由药剂师提供,目前在多个国家常规开展。在此过程中,药剂师会与患者面谈,并与主治医生合作,结合患者的用药史及包括实验室检查结果在内的其他医疗数据,优化患者的药物治疗方案。在最初实施干预措施期间及之后保持此类干预措施质量的必要性再怎么强调也不为过。

目的

本研究的目的是完善并评估一个评分表,以评估比利时社区药房开展的MR3的质量。

方法

使用先前开发的名为BRANT - MERQS(布鲁塞尔安特卫普药物审查质量评分)的评分表,通过对MR3的各个组成部分进行评分来评估其综合质量。从一项针对类风湿性关节炎(RA,子项目1)和2型糖尿病(T2DM,子项目2)患者的实施研究中分析MR3。通过与子项目1中完成首次MR3的部分参与药剂师进行电话沟通,获取了更多信息。

结果

在子项目1中,共检查了21份RA患者的MR3。评估显示,诸如组织良好的用药计划、治疗依从性以及具体干预措施的制定等方面得分较高。然而,某些其他质量标准在评估中带来了挑战,例如使用简单易懂的语言。药剂师面临时间限制,老年全科医生(GP)积极性有限,这些是该子项目中明显的障碍。在子项目2中,对41份T2DM患者的MR3进行了调查,药剂师与GP之间的互动以及所使用的信息来源和工具等质量标准得分较高。然而,仍有改进空间,特别是在准确给药、处理肾功能、QT间期延长、正确将实验室检查结果与相关药物和医疗状况关联以及优化患者用药计划等方面。

结论

本研究证明了通过评分系统对MR3质量进行评估的可行性。然而,它也揭示了该工具目前的不足之处,并强调了持续完善的必要性,这对于处于实施阶段的新服务来说是预期的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9cac/11362585/36686c879e05/fphar-15-1359568-g001.jpg

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