Department of Radiology, Samsung Medical Center, Seoul, Korea.
Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Gut Liver. 2024 Sep 15;18(5):789-802. doi: 10.5009/gnl240350. Epub 2024 Sep 3.
Local ablation for hepatocellular carcinoma, a non-surgical option that directly targets and destroys tumor cells, has advanced significantly since the 1990s. Therapies with different energy sources, such as radiofrequency ablation, microwave ablation, and cryoablation, employ different mechanisms to induce tumor necrosis. The precision, safety, and effectiveness of these therapies have increased with advances in guiding technologies and device improvements. Consequently, local ablation has become the first-line treatment for early-stage hepatocellular carcinoma. The lack of organized evidence and expert opinions regarding patient selection, preprocedure preparation, procedural methods, swift post-treatment evaluation, and follow-up has resulted in clinicians following varied practices. Therefore, an expert consensus-based practical recommendation for local ablation was developed by a group of experts in radiology and hepatology from the Research Committee of the Korean Liver Cancer Association in collaboration with the Korean Society of Image-Guided Tumor Ablation to provide useful information and guidance for performing local ablation and for the pre- and post-treatment management of patients.
自 20 世纪 90 年代以来，针对肝癌的非手术治疗方法——局部消融治疗已经取得了显著进展。该治疗方法通过不同的能量源（如射频消融、微波消融和冷冻消融）直接靶向和破坏肿瘤细胞，采用不同的机制诱导肿瘤坏死。随着引导技术和设备的改进，这些治疗方法的准确性、安全性和有效性都得到了提高。因此，局部消融已经成为早期肝癌的首选治疗方法。由于缺乏有关患者选择、术前准备、手术方法、快速术后评估和随访的系统证据和专家意见，导致临床医生采用了不同的治疗方法。因此，韩国肝癌研究委员会放射学和肝脏病学专家组与韩国影像引导肿瘤消融学会合作，制定了基于专家共识的局部消融实用推荐，为实施局部消融以及患者的术前和术后管理提供了有用的信息和指导。
