Center for Liver and Pancreatobiliary Cancer, National Cancer Center, Goyang, Korea.
Department of Radiology, Seoul National University Hospital, Seoul, Korea.
Korean J Radiol. 2023 Jul;24(7):606-625. doi: 10.3348/kjr.2023.0385.
Transarterial chemoembolization (TACE) was introduced in 1977 with the administration of chemotherapeutic agent to gelatin sponge particles through the hepatic artery in patients with hepatocellular carcinoma (HCC) and was established as conventional TACE using Lipiodol in the 1980s. In the 2000s, drug-eluting beads were developed and applied clinically. Currently, TACE is a commonly used non-surgical treatment modality for patients with HCC who are unsuitable for curative treatment. Considering the vital role of TACE in the management of HCC, it is crucial to organize current knowledge and expert opinions regarding patient preparation, procedural techniques, and post-treatment care in TACE, which can enhance therapeutic efficacy and safety. A group of 12 experts in the fields of interventional radiology and hepatology, convened by the Research Committee of the Korean Liver Cancer Association (KLCA), has developed expert consensus-based practical recommendations in TACE. These recommendations have been endorsed by the Korean Society of Interventional Radiology and provide useful information and direction in performing TACE procedure as well as pre- and post-procedural patient care.
经肝动脉化疗栓塞术(TACE)于 1977 年问世,将化疗药物注入明胶海绵颗粒中,用于治疗肝细胞癌(HCC)患者,并在 20 世纪 80 年代采用碘油确立了常规 TACE。21 世纪初,载药微球研制成功并应用于临床。目前,TACE 是不适合根治性治疗的 HCC 患者的常用非手术治疗方法。考虑到 TACE 在 HCC 管理中的重要作用,有必要组织当前关于 TACE 患者准备、手术技术和治疗后护理的知识和专家意见,以提高治疗效果和安全性。由韩国肝癌协会(KLCA)研究委员会召集的 12 名介入放射学和肝脏病学领域的专家制定了 TACE 基于专家共识的实用建议。这些建议得到了韩国介入放射学会的认可,为 TACE 手术的实施以及术前和术后患者护理提供了有用的信息和指导。