Suppr超能文献

电子烟相关疾病:重新评估

Vaping-associated illness: a reassessment.

作者信息

Schiffman Jonathan S

机构信息

Department of Emergency Medicine, Valley Hospital, 4 Valley Health Plaza, Paramus, NJ, 07652, USA.

出版信息

Int J Emerg Med. 2024 Sep 2;17(1):107. doi: 10.1186/s12245-024-00692-4.

Abstract

BACKGROUND

In 2019, there was widespread presentation of respiratory distress as well as other organ system involvement in patients with a history of vaping. There continue to be reports of vaping-associated illness (VAI). This has come to be known as e-cigarette and vaping product associated lung injury (EVALI). The mechanism of injury remains unclear.

OBJECTIVES

This study reexamines the clinical characteristics of patients affected by vaping and suggests that lung injury may not be the primary organ dysfunction but be part of a larger systemic illness.

METHODS

This is a retrospective chart review of all patients presenting to one hospital identified as having vaping-associated illness RESULTS: Fourteen patients were identified ranging in age from 15 to 33 years. Patients had a broad range of clinical severity. Respiratory symptoms occurred in 64%, gastrointestinal symptoms in 57%, fever in 78%, neurological symptoms in 15% and other constitutional symptoms in 50%. 35% presented with no respiratory symptoms.

CONCLUSION

While the lungs are certainly involved in vaping-associated illness, recognizing the extent of involvement of other organ systems may provide insight into the pathophysiology of the disease. Providers should be aware that vaping-associated illness presents with a multitude of symptoms outside of lung injury, such as abdominal pain, headache or even fever.

摘要

背景

2019年,有吸食电子烟史的患者普遍出现呼吸窘迫以及其他器官系统受累的情况。关于与吸食电子烟相关疾病(VAI)的报道仍在继续。这已被称为电子烟和雾化产品相关肺损伤(EVALI)。损伤机制仍不清楚。

目的

本研究重新审视了受电子烟影响患者的临床特征,并表明肺损伤可能不是主要的器官功能障碍,而是更广泛的全身性疾病的一部分。

方法

这是一项对一家医院所有被确定患有与吸食电子烟相关疾病的患者进行的回顾性病历审查。

结果

确定了14名患者,年龄在15至33岁之间。患者的临床严重程度范围广泛。64%的患者出现呼吸道症状,57%出现胃肠道症状,78%发热,15%出现神经症状,50%出现其他全身症状。35%的患者没有呼吸道症状。

结论

虽然肺部肯定参与了与吸食电子烟相关的疾病,但认识到其他器官系统的受累程度可能有助于深入了解该疾病的病理生理学。医疗服务提供者应意识到,与吸食电子烟相关的疾病除了肺损伤外,还表现为多种症状,如腹痛、头痛甚至发热。

相似文献

1
Vaping-associated illness: a reassessment.
Int J Emerg Med. 2024 Sep 2;17(1):107. doi: 10.1186/s12245-024-00692-4.
2
E-cigarette, or vaping, product use-associated lung injury in adolescents: a review of imaging features.
Pediatr Radiol. 2020 Mar;50(3):338-344. doi: 10.1007/s00247-019-04572-5. Epub 2020 Jan 2.
3
6
E-cigarette or vaping-associated lung injury (EVALI): a review of international case reports from outside the United States of America.
Clin Toxicol (Phila). 2023 Feb;61(2):91-97. doi: 10.1080/15563650.2022.2160342. Epub 2023 Jan 13.
7
E-cigarette or Vaping Product Use-Associated Lung Injury (EVALI) Without Respiratory Symptoms.
Pediatrics. 2020 May;145(5). doi: 10.1542/peds.2019-3408. Epub 2020 Apr 21.
8
A Case Series of E-cigarette or Vaping-Associated Lung Injury With a Review of Pathological and Radiological Findings.
Cureus. 2022 May 8;14(5):e24822. doi: 10.7759/cureus.24822. eCollection 2022 May.
9
E-cigarette or vaping induced lung injury: A case series and literature review.
Toxicol Rep. 2020 Oct 3;7:1381-1386. doi: 10.1016/j.toxrep.2020.09.010. eCollection 2020.

本文引用的文献

2
Electronic cigarette vaping with aged coils causes acute lung injury in mice.
Arch Toxicol. 2022 Dec;96(12):3363-3371. doi: 10.1007/s00204-022-03388-x. Epub 2022 Oct 4.
3
E-cigarette or vaping product use associated lung injury (EVALI) in the time of COVID-19: A clinical dilemma.
Pediatr Pulmonol. 2022 Mar;57(3):623-630. doi: 10.1002/ppul.25804. Epub 2022 Jan 17.
4
EVALI versus MIS-C, one more overlapping diagnosis to consider.
Pediatr Pulmonol. 2021 Sep;56(9):2918-2924. doi: 10.1002/ppul.25558. Epub 2021 Jul 16.
5
A Gut Feeling: Abdominal Symptoms as an Initial Presentation of EVALI.
Pediatrics. 2021 Jan;147(1). doi: 10.1542/peds.2019-3834.
6
Cytokine Storm.
N Engl J Med. 2020 Dec 3;383(23):2255-2273. doi: 10.1056/NEJMra2026131.
7
Non-respiratory presentations of COVID-19, a clinical review.
Am J Emerg Med. 2020 Nov;38(11):2444-2454. doi: 10.1016/j.ajem.2020.09.054. Epub 2020 Sep 24.
8
"Cytokine storm", not only in COVID-19 patients. Mini-review.
Immunol Lett. 2020 Dec;228:38-44. doi: 10.1016/j.imlet.2020.09.007. Epub 2020 Sep 29.
9
E-cigarette or Vaping-Associated Acute Lung Injury and Hemophagocytic Lymphohistiocytosis.
Pediatrics. 2020 Oct;146(4). doi: 10.1542/peds.2019-3664. Epub 2020 Sep 23.
10
Clinical Features of E-cigarette, or Vaping, Product Use-Associated Lung Injury in Teenagers.
Pediatrics. 2020 Jul;146(1). doi: 10.1542/peds.2019-4104. Epub 2020 May 11.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验