Genes encoding ribosomal proteins S16 and L19 form a gene cluster at 56.4 min in Escherichia coli.

A mutant of Escherichia coli which was isolated for temperature-sensitive growth was found to harbour a structural alterations in protein S16 (Isolo et al., 1978). The mutation was localized by matings with various Hfr strains and by Plkc-mediated transduction. The results showed that it mapped very close to the gene coding for L19 protein which has been placed at 56.4 min (Kitakawa and Isono, 1977), indicating that it most likely forms a new ribosomal protein-gene cluster.