实时肿瘤追踪在肝脏肿瘤立体定向容积调强弧形放疗中的临床应用
Clinical application of real-time tumor-tracking for stereotactic volumetric modulated arc therapy for liver tumors.
作者信息
Miyamoto Naoki, Katoh Norio, Kanehira Takahiro, Yokokawa Kohei, Suzuki Ryusuke, Uchinami Yusuke, Taguchi Hiroshi, Abo Daisuke, Aoyama Hidefumi
机构信息
Faculty of Engineering, Hokkaido University, North13, West 8, Kita-ku, Sapporo, Hokkaido 060-8628, Japan.
Department of Medical Physics, Hokkaido University Hospital, North 14, West 5, Kita-ku, Sapporo, Hokkaido 060-8648, Japan.
出版信息
Phys Imaging Radiat Oncol. 2024 Aug 5;31:100623. doi: 10.1016/j.phro.2024.100623. eCollection 2024 Jul.
Real-time tumor-tracking volumetric modulated arc therapy (RT-VMAT) enabling beam-gating based on continuous X-ray tracking of the three-dimensional position of internal markers is relevant for moving tumors. Dose-volume characteristics and treatment time were evaluated in ten consecutive patients who underwent liver stereotactic body radiation therapy with RT-VMAT. Target dose conformity and sparing of the stomach and the intestine were improved comparing RT-VMAT with RT-3D conformal radiotherapy. The mean treatment time for each fraction was less than 10 min. RT-VMAT could be effective, especially for targets located adjacent to organs at risk.
基于内部标记物三维位置的连续X射线跟踪实现束流门控的实时肿瘤跟踪容积调强弧形放疗（RT-VMAT）对移动肿瘤具有重要意义。对连续10例行肝脏立体定向体部放疗的RT-VMAT患者的剂量体积特征和治疗时间进行了评估。与RT-3D适形放疗相比，RT-VMAT改善了靶区剂量适形性以及胃和肠道的保护。每个分割的平均治疗时间不到10分钟。RT-VMAT可能是有效的，特别是对于位于危及器官附近的靶区。
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