衰老对面部-姓名识别的影响：一项 fMRI 研究。
The Effect of Aging on Face-Name Recognition: An fMRI Study.
出版信息
Turk Psikiyatri Derg. 2024 Fall;35(3):214-224. doi: 10.5080/u27095. Epub 2024 Aug 14.
OBJECTIVE
The aim of this study is to detect functional changes in the brain during the memory task with aging and the association between functional changes and memory performance.
METHOD
The study consisted of Young Adult Group (YAG, n=20) aged 20 to 25 and Late Adult Group (LAG, n=18) aged 60 to 70. Individuals with Montreal Cognitive Assessment (MoCA) scores above 21 and no family history of Alzheimer's Disease were included in the study. Functional Magnetic Resonance Imaging (fMRI) scanning was performed on all participants during a memory task including encoding (face and name), face and name recognition sub-tasks.
RESULTS
Results indicated that LAG showed increased activity during face recognition task in left posterior cingulate cortex, left superior frontal cortex, left fusiform face area and another increased activity was found out during name recognition task in left superior frontal cortex, right prefrontal cortex, left anterior + posterior cingulate cortex. The accuracy of face recognition and name recognition memory tests were significantly lower in LAG (respectively, p=0.026; p=0.001).
CONCLUSION
These results indicated that advanced age were associated with more widespread activation in brain during memory task. Thus with aging, individuals require more neuronal and cognitive resources during memory processing.
目的
本研究旨在检测大脑在记忆任务中随年龄变化的功能变化，以及功能变化与记忆表现之间的关系。
方法
研究对象包括青年组（YAG，n=20），年龄在 20 至 25 岁之间；和老年组（LAG，n=18），年龄在 60 至 70 岁之间。所有参与者均接受蒙特利尔认知评估（MoCA）测试，得分高于 21 分且无阿尔茨海默病家族史。在记忆任务（包括编码（面孔和姓名）、面孔和姓名识别子任务）中对所有参与者进行功能磁共振成像（fMRI）扫描。
结果
结果表明，老年组在面孔识别任务中左后扣带回皮质、左额上回、左梭状回面孔区的活动增加，在名称识别任务中左额上回、右前额叶、左前后扣带回的活动增加。老年组在面孔识别和名称识别记忆测试中的准确率明显较低（分别为 p=0.026；p=0.001）。
结论
这些结果表明，随着年龄的增长，大脑在记忆任务中会出现更广泛的激活。因此，随着年龄的增长，个体在记忆处理过程中需要更多的神经元和认知资源。
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