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生活方式干预对西非 2 型糖尿病成人血糖控制效果的系统评价和荟萃分析方案。

Effectiveness of lifestyle interventions for glycaemic control among adults with type 2 diabetes in West Africa: a systematic review and meta-analysis protocol.

机构信息

Ghana College of Physicians and Surgeons, Accra, Ghana.

London School of Hygiene and Tropical Medicine, London, UK.

出版信息

Syst Rev. 2024 Sep 3;13(1):226. doi: 10.1186/s13643-024-02555-8.

DOI:10.1186/s13643-024-02555-8
PMID:39227940
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11370026/
Abstract

BACKGROUND

Lifestyle interventions are key to the control of diabetes and the prevention of complications, especially when used with pharmacological interventions. This protocol aims to review the effectiveness of lifestyle interventions in relation to nutrition and physical activity within the West African region. This systematic review and meta-analysis seeks to understand which interventions for lifestyle modification are implemented for the control of diabetes in West Africa at the individual and community level, what evidence is available on their effectiveness in improving glycaemic control and why these interventions were effective.

METHODS

We will review randomised control trials and quasi-experimental designs on interventions relating to physical activity and nutrition in West Africa. Language will be restricted to English and French as these are the most widely spoken languages in the region. No other filters will be applied. Searching will involve four electronic databases - PubMed, Scopus, Africa Journals Online and Cairn.info using natural-language phrases plus reference/citation checking. Two reviewers will independently screen results according to titles and abstracts against the inclusion and exclusion criteria to identify eligible studies. Upon full-text review, all selected studies will be assessed using Cochrane's Collaboration tool for assessing the risk of bias of a study and the ROBINS-I tool before data extraction. Evidence will be synthesised narratively and statistically where appropriate. We will conduct a meta-analysis when the interventions and contexts are similar enough for pooling and compare the treatment effects of the interventions in rural to urban settings and short term to long term wherever possible.

DISCUSSION

We anticipate finding a number of studies missed by previous reviews and providing evidence of the effectiveness of different nutrition and physical activity interventions within the context of West Africa. This knowledge will support practitioners and policymakers in the design of interventions that are fit for context and purpose within the West African region.

SYSTEMATIC REVIEW REGISTRATION

This systematic review has been registered in the International Prospective Register for Systematic Reviews - PROSPERO, with registration number CRD42023435116. All amendments to this protocol during the process of the review will be explained accordingly.

摘要

背景

生活方式干预是控制糖尿病和预防并发症的关键,尤其是与药物干预联合使用时。本方案旨在回顾西非地区与营养和身体活动相关的生活方式干预的有效性。本系统评价和荟萃分析旨在了解在个体和社区层面上,为控制糖尿病在西非实施了哪些生活方式改变干预措施,有哪些证据表明这些干预措施在改善血糖控制方面有效,以及为什么这些干预措施有效。

方法

我们将综述与西非身体活动和营养相关的干预措施的随机对照试验和准实验设计。语言将限于英语和法语,因为这两种语言是该地区使用最广泛的语言。不会应用其他过滤器。搜索将涉及四个电子数据库 - PubMed、Scopus、Africa Journals Online 和 Cairn.info,使用自然语言短语加参考/引文检查。两名审查员将根据纳入和排除标准独立筛选标题和摘要的结果,以确定符合条件的研究。在全文审查后,所有选定的研究将使用 Cochrane 协作工具评估研究偏倚风险和 ROBINS-I 工具进行评估,然后进行数据提取。将根据需要以叙述和统计方式综合证据。如果干预措施和背景足够相似,可以进行荟萃分析,并比较农村和城市环境以及短期和长期干预措施的治疗效果。

讨论

我们预计会发现以前综述遗漏的一些研究,并提供在西非背景下不同营养和身体活动干预措施有效性的证据。这方面的知识将支持从业者和决策者在西非地区设计适合背景和目的的干预措施。

系统评价注册

本系统评价已在国际前瞻性系统评价注册库(PROSPERO)中注册,注册编号为 CRD42023435116。在审查过程中,本方案的所有修订都将相应解释。

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