Pierce Anna
Department of Infectious Diseases, The Alfred Hospital, Melbourne.
Department of Infectious Diseases, Monash Health, Melbourne.
Aust Prescr. 2024 Aug;47(4):113-118. doi: 10.18773/austprescr.2024.037.
Primary care workplaces where occupational exposure to blood and body fluids may occur should have policies and procedures in place to manage such incidents. All healthcare workers should be immunised against hepatitis B and ideally should have documentation of their antibody response to vaccination. Knowledge of hepatitis B immune status helps streamline the response to any exposure. Most occupational exposures carry a low risk of transmission of bloodborne viruses, and management can often be undertaken in general practice. Urgent risk assessment and management is crucial. If postexposure prophylaxis for hepatitis B or HIV is required, the earlier it is given, the more likely it is to be effective. Two-drug HIV postexposure prophylaxis is now more accessible because generic formulations of the drug combination are available, and general practitioners can prescribe this on a private prescription.
可能发生职业性血液和体液暴露的基层医疗工作场所应制定相关政策和程序来处理此类事件。所有医护人员都应接种乙肝疫苗,理想情况下应有其对疫苗抗体反应的记录。了解乙肝免疫状况有助于简化对任何暴露情况的应对。大多数职业暴露传播血源性病原体的风险较低,通常可在全科医疗中进行处理。紧急风险评估和管理至关重要。如果需要进行乙肝或艾滋病毒暴露后预防,给药越早,越有可能有效。由于有该药物组合的通用配方,现在两种药物的艾滋病毒暴露后预防更容易获得,全科医生可以凭私人处方开具此药。