Kadir Nik A Nik Abdul, Abdul-Razak Suraya, Daher Aqil M, Nasir Nafiza Mat
Department of Primary Care Medicine, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh Campus, Sungai Buloh, Selangor, Malaysia.
Cardiovascular and Lungs Research Institute (CaVaLRI), Hospital Al-Sultan Abdullah UiTM, Sungai Buloh Campus, Sungai Buloh, Selangor, Malaysia.
J Family Med Prim Care. 2024 Aug;13(8):2900-2911. doi: 10.4103/jfmpc.jfmpc_1761_23. Epub 2024 Jul 26.
Erectile dysfunction (ED) is an independent predictor for cardiovascular diseases (CVD). The prevalence increases with age, but little is known about the relationship between handgrip strength (HGS) and ED, especially among men with a high risk of CVD. This study aimed to determine the prevalence of ED among men aged ≥40 years with metabolic syndrome (MetS) and its association with HGS.
A cross-sectional study at an institutional primary care clinic in Malaysia was conducted between June 2021 and October 2021. HGS and erectile function were assessed using a hand dynamometer and International Index of Erectile Function (IIEF-5) questionnaire, respectively. Multiple logistic regression analyses were performed to determine the association between sociodemographics, clinical characteristics, and HGS with ED.
A total of 334 participants were recruited. The prevalence of ED was 79% (95% confidence interval [CI]: 0.75-0.84). ED was associated with elderly aged ≥60 years (odds ratio [OR] 3.27, 95%CI: 1.60-6.69), low HGS (OR 15.34, 95%CI: 5.64-41.81) and high total cholesterol (OR 0.36, 95%CI: 0.16-0.78).
In conclusion, age above 60 years and those with low HGS are at higher risk of ED. Thus, robust screening of ED among men with MetS and improving muscle strength and physical fitness may be warranted.
勃起功能障碍（ED）是心血管疾病（CVD）的独立预测指标。其患病率随年龄增长而增加，但关于握力（HGS）与ED之间的关系，尤其是在心血管疾病高危男性中的关系，人们了解甚少。本研究旨在确定≥40岁代谢综合征（MetS）男性中ED的患病率及其与握力的关联。
2021年6月至2021年10月在马来西亚一家机构初级保健诊所进行了一项横断面研究。分别使用握力计和国际勃起功能指数（IIEF-5）问卷评估握力和勃起功能。进行多因素逻辑回归分析以确定社会人口统计学、临床特征和握力与勃起功能障碍之间的关联。
共招募了334名参与者。勃起功能障碍的患病率为79%（95%置信区间[CI]：0.75-0.84）。勃起功能障碍与≥60岁的老年人（优势比[OR] 3.27，95%CI：1.60-6.69）、低握力（OR 15.34，95%CI：5.64-41.81）和高总胆固醇（OR 0.36，95%CI：0.16-0.78）相关。
总之，60岁以上且握力低的人群患勃起功能障碍的风险更高。因此，对患有代谢综合征的男性进行强有力的勃起功能障碍筛查以及改善肌肉力量和身体素质可能是必要的。
