Khan Raveed, St Hill Ramona, Awe Olusegun, Bhola O'Reon, Orumwense Osayimwense, Deosaran Pavitra, Seecharan Priya, Avula Puneeth, Mohammed Rafiah, Terapalli Ashni, Jardine Rebecca M
Department of Para Clinical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad, West Indies.
School of Medicine, The University of the West Indies, St. Augustine, Trinidad, West Indies.
J Family Med Prim Care. 2024 Aug;13(8):3214-3219. doi: 10.4103/jfmpc.jfmpc_1895_23. Epub 2024 Jul 26.
This study describes the characteristics of men attending a primary health care screening initiative, determines the proportion of men who have elevated International Prostate Symptom Score (IPSS) scores and prostate-specific antigen (PSA) levels, and determines any correlation between these scores as indicators for benign prostatic hyperplasia (BPH) or prostate cancer.
Data were collected from all patient records during men's health screening initiatives that occurred in December 2018, January 2019, and March 2019 in Trinidad and Tobago. A total of 350 medical records were analyzed to record patient demographics, PSA levels, and IPSS scores. Analysis of the data was performed with the use of Statistical Package for the Social Sciences software (version 27).
Most men who attended the screening initiative belonged to the 61-65 age group (20.57%), with more than half of the men being married (57.71%) and employed (52.57%) and of patients with comorbidities (17%), the most prevalent included hypertension (6%) and diabetes mellitus (3.7%). A mean PSA level of 2.94 ng/ml and a mean IPSS of 7.62 were recorded. Moreover, 11.5% of the males had elevated PSA levels (>4 ng/ml) and 32.9% had elevated IPSS levels (>8). There were correlations between PSA and IPSS values (r = 0.161 and = 0.006). Age was a predictor of both IPSS and PSA values (r = 0.214, = 0.000 and r = 0.192, = 0.000, respectively). Among diabetic participants, a small but significant correlation between IPSS and diabetes was shown (r = 0.223, = 0.028). As a predictor of elevated IPSS, diabetes had an odds ratio of 1.132 (95% confidence interval (CI): 1.021-1.255).
Our findings are similar to those described in previous studies; however, further investigations are required to fully describe the relationship between PSA and IPSS. This may assist in advancing screening measures and improving health outcomes for men with BPH and prostate cancer. Primary care physicians should recognize the possible association between BPH and diabetes mellitus and offer appropriate screening where indicated.
本研究描述了参加初级卫生保健筛查项目的男性的特征，确定国际前列腺症状评分（IPSS）升高和前列腺特异性抗原（PSA）水平升高的男性比例，并确定这些评分之间作为良性前列腺增生（BPH）或前列腺癌指标的任何相关性。
收集了2018年12月、2019年1月和2019年3月在特立尼达和多巴哥进行的男性健康筛查项目期间所有患者记录的数据。共分析了350份病历，以记录患者的人口统计学信息、PSA水平和IPSS评分。使用社会科学统计软件包（第27版）对数据进行分析。
参加筛查项目的大多数男性属于61 - 65岁年龄组（20.57%），超过一半的男性已婚（57.71%）且就业（52.57%），在有合并症的患者中（17%），最常见的包括高血压（6%）和糖尿病（3.7%）。记录的平均PSA水平为2.94 ng/ml，平均IPSS为7.62。此外，11.5%的男性PSA水平升高（>4 ng/ml），32.9%的男性IPSS水平升高（>8）。PSA和IPSS值之间存在相关性（r = 0.161，P = 0.006）。年龄是IPSS和PSA值的预测因素（分别为r = 0.214，P = 0.000和r = 0.192，P = 0.000）。在糖尿病参与者中，IPSS与糖尿病之间显示出小但显著的相关性（r = 0.223，P = 0.028）。作为IPSS升高的预测因素，糖尿病的比值比为1.132（95%置信区间（CI）：1.021 - 1.255）。
我们的研究结果与先前研究中描述的结果相似；然而，需要进一步调查以充分描述PSA和IPSS之间的关系。这可能有助于推进筛查措施并改善BPH和前列腺癌男性的健康结果。初级保健医生应认识到BPH与糖尿病之间可能的关联，并在有指征时提供适当的筛查。
