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从新冠病毒2型(SARS-CoV-2)快速抗原检测阴性样本中进行呼吸道病毒检测与测序

Respiratory virus detection and sequencing from negative SARS-CoV-2 rapid antigen tests.

作者信息

Jules Emmanuela, Decker Charlie, Bixler Brianna Jeanne, Ahmed Alaa, Zhou Zijing Carol, Arora Itika, Tafesse Henok, Dakanay Hannah, Bombin Andrei, Wang Ethan, Ingersoll Jessica, Bifulco Kathy, Frediani Jennifer K, Parsons Richard, Sullivan Julie, Greenleaf Morgan, Waggoner Jesse J, Martin Greg S, Lam Wilbur A, Piantadosi Anne

机构信息

Department of Pathology and Laboratory Medicine; Emory University School of Medicine; Atlanta, GA, 30322; USA.

Division of Infectious Diseases; Department of Medicine, Emory University School of Medicine; Atlanta, GA, 30322; USA.

出版信息

medRxiv. 2024 Aug 20:2024.08.19.24311993. doi: 10.1101/2024.08.19.24311993.

Abstract

Genomic epidemiology offers important insight into the transmission and evolution of respiratory viruses. We used metagenomic sequencing from negative SARS-CoV-2 antigen tests to identify a wide range of respiratory viruses and generate full genome sequences, offering a streamlined mechanism for broad respiratory virus genomic surveillance.

摘要

基因组流行病学为深入了解呼吸道病毒的传播和进化提供了重要视角。我们利用来自新冠病毒抗原检测阴性样本的宏基因组测序来鉴定多种呼吸道病毒并生成全基因组序列,为广泛的呼吸道病毒基因组监测提供了一种简化机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c077/11370544/75f734d1a8f1/nihpp-2024.08.19.24311993v1-f0001.jpg

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