Kobayashi Taku, Iwasaki Takatoshi, Kurata Hiroko, Nikaido Akira, Hata Yoshiki
Department of Rehabilitation, Minamino Cardiovascular Hospital, Japan.
Hachioji Minamino Cardiac Rehabilitation Clinic, Japan.
Int J Cardiol Heart Vasc. 2024 Jun 13;53:101442. doi: 10.1016/j.ijcha.2024.101442. eCollection 2024 Aug.
In Japan, the number of very elderly individuals with heart failure (HF) is on the rise. One indicator of HF stage progression is a decrease in exercise tolerance (ET). While peak oxygen uptake (peak VO₂) determined by cardiopulmonary exercise testing (CPX) is the gold standard for ET assessment, the wide-scale applicability of CPX is constrained owing to expensive equipment and challenges in this population. The 30-second chair stand test (CS30), a simple and quick alternative, is widely used among community-dwelling elderly individuals. The objective of this study was to investigate whether CS30 is a predictor of ET in elderly individuals with stage A/B HF.
Of 748 outpatients aged 75 years and over who visited our center between March 2021 and December 2022, 493 patients (296 males and 197 females) were included in this study. CS30 was measured using a seat height of 40 cm, and peak VO₂ was assessed using CPX.
The findings showed a statistically significant positive association between CS30 and peak VO₂ for both males and females (males: β = 0.255, 95 % CI = 0.102-0.407; females: β = 0.282, 95 % CI = 0.043-0.521). Receiver operating characteristic (ROC) analyses showed moderate accuracy of CS30 in predicting low ET in both sexes (males AUC = 0.740, 95 % CI = 0.640-0.841, p < 0.001; females AUC = 0.725, 95 % CI = 0.644-0.807, p < 0.001). The cut-off values of CS30 were established as 18 times for males and 16 times for females.
CS30 is a potentially convenient method for estimating current ET in older adults, providing a feasible alternative to CPX.
在日本,患有心力衰竭(HF)的高龄个体数量正在增加。心力衰竭阶段进展的一个指标是运动耐量(ET)下降。虽然通过心肺运动试验(CPX)测定的峰值摄氧量(peak VO₂)是评估运动耐量的金标准,但由于设备昂贵以及在该人群中存在的挑战,CPX的广泛应用受到限制。30秒坐立试验(CS30)是一种简单快捷的替代方法,在社区居住的老年人中广泛使用。本研究的目的是调查CS30是否是A/B期心力衰竭老年个体运动耐量的预测指标。
在2021年3月至2022年12月期间访问我们中心的748名75岁及以上的门诊患者中,493例患者(296例男性和197例女性)纳入本研究。CS30使用40厘米的座椅高度进行测量,peak VO₂使用CPX进行评估。
研究结果显示,男性和女性的CS30与peak VO₂之间均存在统计学上显著的正相关(男性:β = 0.255,95%CI = 0.102 - 0.407;女性:β = 0.282,95%CI = 0.043 - 0.521)。受试者工作特征(ROC)分析表明,CS30在预测两性低运动耐量方面具有中等准确性(男性AUC = 0.740,95%CI = 0.640 - 0.841,p < 0.001;女性AUC = 0.725,95%CI = 0.644 - 0.807,p < 0.001)。CS30的截断值确定为男性18次,女性16次。
CS30是一种潜在方便的方法,可用于估计老年人当前的运动耐量,为CPX提供了一种可行的替代方法。