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一种被忽视的疾病:化脓性汗腺炎——淀粉样变性合并脓毒症及肾衰竭的罕见病因:一例报告

A Neglected Disease: Hidradenitis Suppurativa a Rare Cause of Amyloidosis Complicated With Sepsis and Renal Failure: A Case Report.

作者信息

Demir Orhun, Yondem Omer Zuhtu, Doganay Mehmet

机构信息

Department of Anesthesiology Faculty of Medicine Lokman Hekim University, Ankara, Türkiye.

Department of Infectious Diseases Faculty of Medicine Lokman Hekim University, Ankara, Türkiye.

出版信息

Case Rep Crit Care. 2024 Aug 27;2024:4893040. doi: 10.1155/2024/4893040. eCollection 2024.

Abstract

Hidradenitis suppurativa (HS) is a painful relapsing inflammatory disease characterized with subcutaneous nodules, abscesses, tunnels, and deforming scars. We present a case of HS complicated with amyloidosis who was admitted with sepsis and acute renal failure. A 53-year-old male patient with a history of HS and amyloidosis was accepted to the intensive care unit suffering from acute kidney failure and sepsis symptoms. He was receiving adalimumab during admission. He received hemodialysis and piperacillin-tazobactam antibiotherapy. After 15 days of hospitalization, his sepsis was treated, but he was taken to a routine hemodialysis programme. In the presence of amyloidosis with intervenient infections, the risk of chronic renal failure in HS cases can be kept in mind even if the patient is receiving TNF inhibitors.

摘要

化脓性汗腺炎(HS)是一种疼痛性复发性炎症性疾病,其特征为皮下结节、脓肿、窦道和变形瘢痕。我们报告一例HS合并淀粉样变性的病例,该患者因脓毒症和急性肾衰竭入院。一名有HS和淀粉样变性病史的53岁男性患者因急性肾衰竭和脓毒症症状入住重症监护病房。入院期间他正在接受阿达木单抗治疗。他接受了血液透析和哌拉西林-他唑巴坦抗菌治疗。住院15天后,他的脓毒症得到治疗,但随后被纳入常规血液透析方案。在存在淀粉样变性并伴有间歇性感染的情况下,即使患者正在接受肿瘤坏死因子抑制剂治疗,HS病例发生慢性肾衰竭的风险也应予以考虑。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3669/11371454/0152acdbc2a9/CRICC2024-4893040.001.jpg

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