Diagnosis, treatment and burden in advanced ovarian cancer: a UK real-world survey of healthcare professionals and patients.

Little is known regarding uptake of epithelial ovarian cancer (EOC) treatments or patient burden in UK real-world practice. Cross-sectional surveys of patients with advanced EOC and healthcare professionals (HCPs). 101 HCPs and 142 patients participated. Time from initial primary care consultation to diagnosis was ∼7 weeks. 83% patients were offered hereditary genetic testing, with 89% uptake. 53% HCPs reported surgery was performed ≤1 month in non-neoadjuvant setting. Surgery delay negatively impacted patient quality of life (61%), mental health (89%), and surgical outcomes (63%). 56% patients received active first-line maintenance treatment; patients on active surveillance had greater emotional/psychological distress. Treatment delays and low uptake of active first-line treatment should be addressed. Emotional support must be readily accessible throughout treatment.