Choudhury Sunirmal, Ahmed Shahbaaz, Sasmal Surajit, Patel Prakhar
Department of Urology, Medical College and Hospital Kolkata, Kolkata, India.
Urologia. 2025 Feb;92(1):39-43. doi: 10.1177/03915603241277914. Epub 2024 Sep 4.
Urinary bladder tumors are one of the most common urological malignancies. Traditionally, it has been initially managed with conventional trans-urethral resection of urinary bladder tumors (cTURBT) which has certain drawbacks and complications. Efforts have been made to find newer methods for management. In this study, we have used low power Holmium laser en-bloc resection and have assessed its safety, efficacy and feasibility.
Forty patients have been included in this prospective observational study who underwent low power Holmium laser en-bloc resection of urinary bladder tumor after taking Institutional ethical committee clearance and informed consent from all the patients. Intra-operative and post-operative data were collected.
The average tumor size was 21.68 ± 9.55 mm. Out of those, 65% of the patients had a tumor less than 3 cm in size. Fourteen patients (35%) had tumors at multiple sites. The average duration of resection per tumor was 24.84 ± 6.83 min. None of the cases required conversion to cTURBT. There was no obturator reflex or urinary bladder perforation in any of the cases. Detrusor muscle was present in the histopathology reports of 92.5% patients. The average duration of catheterization was 1.82 ± 0.61 days.
For NMIBC's, low power Holmium laser en-bloc resection is a safe procedure with minimum risk of complications. High rate of detrusor-positive specimens indicates its efficacy and feasibility.
膀胱肿瘤是最常见的泌尿外科恶性肿瘤之一。传统上,其初始治疗采用传统经尿道膀胱肿瘤切除术(cTURBT),该方法存在一定缺点和并发症。人们一直在努力寻找新的治疗方法。在本研究中,我们采用了低功率钬激光整块切除术,并评估了其安全性、有效性和可行性。
本前瞻性观察性研究纳入了40例患者,这些患者在获得机构伦理委员会批准并取得所有患者的知情同意后,接受了低功率钬激光膀胱肿瘤整块切除术。收集了术中及术后数据。
肿瘤平均大小为21.68±9.55毫米。其中,65%的患者肿瘤大小小于3厘米。14例患者(35%)肿瘤位于多个部位。每个肿瘤的平均切除时间为24.84±6.83分钟。所有病例均无需转为cTURBT。所有病例均未出现闭孔神经反射或膀胱穿孔。92.5%患者的组织病理学报告中存在逼尿肌。平均导尿时间为1.82±0.61天。
对于非肌层浸润性膀胱癌(NMIBC),低功率钬激光整块切除术是一种安全的手术,并发症风险最低。高比例的逼尿肌阳性标本表明了其有效性和可行性。