高温通过 VI 型分泌系统增加了弧菌对珊瑚宿主和竞争细菌的毒力。
High temperatures increase the virulence of Vibrio bacteria towards their coral host and competing bacteria via type VI secretion systems.
机构信息
Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China.
University of Chinese Academy of Sciences, Beijing, China.
出版信息
PLoS Biol. 2024 Sep 4;22(9):e3002788. doi: 10.1371/journal.pbio.3002788. eCollection 2024 Sep.
Abstract
The bacterial pathogen Vibrio coralliilyticus induces severe coral diseases in warming oceans. A study in PLOS Biology reveals that high temperatures activate 2 type VI secretion systems in V. coralliilyticus, enhancing pathogenicity by deploying toxic effectors against competing bacteria and coral cells.
摘要
细菌性病原体珊瑚弧菌在变暖的海洋中引发严重的珊瑚疾病。一项发表在《公共科学图书馆·生物学》上的研究表明，高温激活了珊瑚弧菌中的 2 种类型 VI 分泌系统，通过针对竞争细菌和珊瑚细胞的毒性效应物来增强致病性。
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