颌部黏液瘤中的糖胺聚糖：一项生化研究。

Glycosaminoglycans in myxoma of the jaw: a biochemical study.

作者信息

Slootweg P J, van den Bos T, Straks W

出版信息

J Oral Pathol. 1985 Apr;14(4):299-306. doi: 10.1111/j.1600-0714.1985.tb00497.x.

DOI:10.1111/j.1600-0714.1985.tb00497.x

Abstract

Myxoma of the jaw is classified as an odontogenic tumor although final proof for an odontogenic origin is lacking. In the present study glycosaminoglycans (GAG's) in the extracellular matrix of a jaw myxoma were analyzed and compared with known data on GAG's in dental tissues. It was noted that the GAG's formed approximately 1% of the total tumor weight and 17% of the dry weight. Hyaluronic acid formed 72.4% of the GAG-fraction. Neither this high GAG-content nor the high fraction of hyaluronic acid are found in dental tissues and it is concluded that the myxoma matrix differs from the matrix in dental pulp and periodontal ligament.

摘要

颌骨黏液瘤虽缺乏牙源性起源的确切证据，但仍被归类为牙源性肿瘤。在本研究中，分析了颌骨黏液瘤细胞外基质中的糖胺聚糖（GAG），并与牙齿组织中GAG的已知数据进行了比较。结果表明，GAG约占肿瘤总重量的1%，占干重的17%。透明质酸占GAG组分的72.4%。在牙齿组织中未发现如此高的GAG含量和高比例的透明质酸，因此得出结论，黏液瘤基质与牙髓和牙周韧带中的基质不同。