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Immunological studies in trans-individuals undergoing gender affirming hormone therapy.

作者信息

James Anna, Brodin Petter

机构信息

Unit for Clinical Pediatrics, Dept. of Women's and Children's Health, Karolinska Institutet, Solna, Sweden.

Medical Research Council Laboratory of Medical Sciences (MRC LMS), Imperial College Hammersmith Campus, London, UK.

出版信息

Nat Rev Immunol. 2024 Oct;24(10):697-698. doi: 10.1038/s41577-024-01070-0.

DOI:10.1038/s41577-024-01070-0
PMID:39232175
Abstract
摘要

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本文引用的文献

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The conneXion between sex and immune responses.性与免疫反应之间的联系。
Nat Rev Immunol. 2024 Jul;24(7):487-502. doi: 10.1038/s41577-024-00996-9. Epub 2024 Feb 21.
2
Reduction of IFN-I responses by plasmacytoid dendritic cells in a longitudinal trans men cohort.纵向跨性别男性队列中浆细胞样树突状细胞对I型干扰素反应的降低
iScience. 2023 Oct 13;26(11):108209. doi: 10.1016/j.isci.2023.108209. eCollection 2023 Nov 17.
3
Analysis of transcriptional changes in the immune system associated with pubertal development in a longitudinal cohort of children with asthma.
分析哮喘儿童纵向队列中与青春期发育相关的免疫系统转录变化。
Nat Commun. 2023 Jan 16;14(1):230. doi: 10.1038/s41467-022-35742-z.
4
Investigating sex differences in T regulatory cells from cisgender and transgender healthy individuals and patients with autoimmune inflammatory disease: a cross-sectional study.调查顺性别和跨性别健康个体以及自身免疫性炎症疾病患者中调节性T细胞的性别差异：一项横断面研究。
Lancet Rheumatol. 2022 Aug 31;4(10):e710-e724. doi: 10.1016/S2665-9913(22)00198-9. eCollection 2022 Oct.
5
Hematopoietic loss of Y chromosome leads to cardiac fibrosis and heart failure mortality.Y 染色体造血细胞丢失导致心脏纤维化和心力衰竭死亡。
Science. 2022 Jul 15;377(6603):292-297. doi: 10.1126/science.abn3100. Epub 2022 Jul 14.
6
Escape from X Chromosome Inactivation and the Female Predominance in Autoimmune Diseases.从 X 染色体失活中逃脱和自身免疫性疾病中的女性优势。
Int J Mol Sci. 2021 Jan 23;22(3):1114. doi: 10.3390/ijms22031114.
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Immune determinants of COVID-19 disease presentation and severity.COVID-19 疾病表现和严重程度的免疫决定因素。
Nat Med. 2021 Jan;27(1):28-33. doi: 10.1038/s41591-020-01202-8. Epub 2021 Jan 13.
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Lupus nephritis in a transgender woman on cross-sex hormone therapy: a case for the role of oestrogen in systemic lupus erythematosus.跨性别激素治疗女性狼疮肾炎：雌激素在系统性红斑狼疮中作用的案例。
Lupus. 2020 Nov;29(13):1807-1810. doi: 10.1177/0961203320946372. Epub 2020 Jul 30.
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Sex and Pubertal Differences in the Type 1 Interferon Pathway Associate With Both X Chromosome Number and Serum Sex Hormone Concentration.性和青春期差异与 1 型干扰素途径相关，同时与 X 染色体数量和血清性激素浓度相关。
Front Immunol. 2019 Jan 15;9:3167. doi: 10.3389/fimmu.2018.03167. eCollection 2018.
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