Institute of Physics, University of Belgrade, Belgrade, Serbia; Mathematical Institute of the Serbian Academy of Sciences and Arts, Belgrade, Serbia.
Research and Development Institute Lola Ltd, Kneza Višeslava 70a, Belgrade, Serbia.
Biosystems. 2024 Dec;246:105322. doi: 10.1016/j.biosystems.2024.105322. Epub 2024 Sep 2.
The genetic code plays a central role in all living organisms and its modeling is important for describing and understanding involved the coding rules. There are many approaches to modeling various aspects of the genetic code. One of the simple and successful mathematical tools for modeling the similarity both between codons and between amino acids, is the ultrametrics and especially the p-adic distance. This article contains an overview of ultrametric (p-adic) modeling of genetic information, and its translation to proteins using the genetic code.
遗传密码在所有生物体中都起着核心作用,其建模对于描述和理解所涉及的编码规则非常重要。有许多方法可以对遗传密码的各个方面进行建模。超度量(p-进数)距离是一种简单而成功的数学工具,可用于对密码子之间和氨基酸之间的相似性进行建模。本文概述了遗传信息的超度量(p-进数)建模,以及使用遗传密码将其翻译为蛋白质。