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单阶段自体-异体联合软骨修复:手术技术

Single-Stage Combined Autologous-Allogenic Cartilage Restoration: Surgical Technique.

作者信息

Swift Brendan, Zhang Ting, Akhter Fauzan, Chilelli Brian J

机构信息

Mercy Health-Cincinnati Sports Medicine and Orthopaedic Center, Cincinnati SportsMedicine Research and Education Foundation, Cincinnati, Ohio, U.S.A.

出版信息

Arthrosc Tech. 2024 May 15;13(8):103024. doi: 10.1016/j.eats.2024.103024. eCollection 2024 Aug.

Abstract

Articular cartilage injuries in young patients pose a notable treatment dilemma. Multiple reported techniques exist, although some of the most prominent methods currently rely on multiple procedures for chondrocyte harvest and colony expansion prior to implantation. The associated cost and effort this requires limits availability on a global basis, which creates a need for a more widely available cartilage procedure. This Technical Note describes a method for cartilage restoration that incorporates autologous chondrocytes in allogenic extracellular matrix, along with biologic augmentation all performed in a single stage.

摘要

年轻患者的关节软骨损伤带来了显著的治疗难题。虽然目前有多种报道的技术,但一些最突出的方法在植入前需要多个程序来采集软骨细胞并进行集落扩增。这所需的相关成本和精力限制了全球范围内的可及性,因此需要一种更广泛可用的软骨修复程序。本技术说明描述了一种软骨修复方法,该方法将自体软骨细胞整合到异体细胞外基质中,并在单个阶段完成生物增强。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4b7/11369936/a19a66e5296a/gr1.jpg

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