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一名年轻男性甲状腺功能亢进合并肾上腺皮质功能不全的非典型表现及成功治疗

Atypical Presentation and Successful Management of Combined Hyperthyroidism and Adrenal Insufficiency in a Young Male.

作者信息

Khalil Zeyad, Hussein Reham E, Al-Abbedien Eman Z

机构信息

College of Medicine, October 6th university, Cairo, EGY.

College of Medicine, October 6th University, Cairo, EGY.

出版信息

Cureus. 2024 Aug 4;16(8):e66150. doi: 10.7759/cureus.66150. eCollection 2024 Aug.

DOI:10.7759/cureus.66150
PMID:39233957
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11372323/
Abstract

This case report details the unusual presentation and successful management of a 25-year-old male diagnosed with both hyperthyroidism and adrenal insufficiency. The patient initially presented with symptoms of fatigue, weight loss, and palpitations, with no significant past medical history. Further evaluation revealed elevated thyroid hormone levels and decreased cortisol levels, confirming the diagnosis of concurrent hyperthyroidism and adrenal insufficiency. The complexity of managing these coexisting endocrine disorders required a multidisciplinary approach. Techniques utilized included detailed hormonal assays, imaging studies, and dynamic endocrine testing. The therapeutic regimen involved the administration of antithyroid medications, beta-blockers for symptom control, and glucocorticoid replacement therapy. This report underscores the importance of considering multiple endocrine disorders in patients with nonspecific systemic symptoms and highlights the need for individualized treatment plans to address the unique challenges presented by such comorbidities.

摘要

本病例报告详细介绍了一名25岁男性同时被诊断为甲状腺功能亢进和肾上腺功能不全的不寻常表现及成功治疗情况。患者最初出现疲劳、体重减轻和心悸症状,既往无重大病史。进一步检查发现甲状腺激素水平升高,皮质醇水平降低,确诊为同时存在甲状腺功能亢进和肾上腺功能不全。管理这些并存的内分泌疾病的复杂性需要多学科方法。所采用的技术包括详细的激素检测、影像学检查和动态内分泌测试。治疗方案包括使用抗甲状腺药物、用于控制症状的β受体阻滞剂以及糖皮质激素替代疗法。本报告强调了在有非特异性全身症状的患者中考虑多种内分泌疾病的重要性,并突出了制定个性化治疗方案以应对此类合并症所带来的独特挑战的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d961/11372323/939a135877c5/cureus-0016-00000066150-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d961/11372323/67f6b8b3b19a/cureus-0016-00000066150-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d961/11372323/d91cb93e9449/cureus-0016-00000066150-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d961/11372323/ffeb0d2e5304/cureus-0016-00000066150-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d961/11372323/939a135877c5/cureus-0016-00000066150-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d961/11372323/67f6b8b3b19a/cureus-0016-00000066150-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d961/11372323/d91cb93e9449/cureus-0016-00000066150-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d961/11372323/ffeb0d2e5304/cureus-0016-00000066150-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d961/11372323/939a135877c5/cureus-0016-00000066150-i04.jpg

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