Suppr超能文献

额叶闭唇型脑裂畸形作为成人癫痫发作的非典型病因。

Frontal lobe closed-lip schizencephaly as an atypical cause of adult-onset seizures.

作者信息

Mousa Ahmed Hafez, Abuanza Imad A M, Al-Olama Mohammad

机构信息

Department of Neurosurgery, Graduate Medical Education, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai Health, Dubai, United Arab Emirates.

Department of Neurosurgery, Rashid Hospital, Dubai Health, Dubai, United Arab Emirates.

出版信息

Radiol Case Rep. 2024 Aug 14;19(11):4890-4893. doi: 10.1016/j.radcr.2024.07.046. eCollection 2024 Nov.

Abstract

Schizencephaly arises from irregular neuronal migration leading to clefts development in the cerebral cortex. The condition is often detected in childhood and it is extremely rare to go unnoticed. This case highlights a 45-year-old male with no previous medical history who presented with a seizure for the first time in the emergency department after which an MRI was done and detected schizcenphaly which at this point was the first time for the patient to be diagnosed with this condition. The available data on schizcencphaly in the literature is very little and the data on the condition when diagnosed in adulthood is even less, hence our case report aims to shed light on this unthought etiology of adult-onset seizures which could have major potential risks if not detected. Adults who receive a diagnoses later in life may face prognosis issues hence imaging should be encouraged to be a part of seizure workup to avoid underdiagnoses of brain abnormalities that may go unnoticed in childhood.

摘要

脑裂畸形源于不规则的神经元迁移,导致大脑皮质出现裂隙。这种情况常在儿童期被发现,极少被漏诊。本病例为一名45岁男性,既往无病史,因首次在急诊科出现癫痫发作就诊,之后进行了磁共振成像(MRI)检查,发现了脑裂畸形,这是该患者首次被诊断出患有此病。文献中关于脑裂畸形的可用数据非常少,关于成年期诊断出该疾病的数据更少,因此我们的病例报告旨在阐明这种成人癫痫发作的罕见病因,如果未被发现可能存在重大潜在风险。成年后才被诊断出患有该病的患者可能面临预后问题,因此应鼓励将影像学检查作为癫痫检查的一部分,以避免漏诊儿童期可能未被注意到的脑部异常。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26bd/11372575/d9b6122ac478/gr1.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验