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医生和患者对生物类似药的认知以及在选定亚洲国家影响生物类似药处方的因素:一项调查研究。

Physicians' and patients' perception of biosimilars and factors affecting biosimilar prescribing in selected Asian countries: a survey study.

机构信息

Internal Medicine - Rheumatology, Bumrungrad International Hospital, Bangkok, Thailand.

Department of Dermatology, KPC, Medical College, West Bengal, India.

出版信息

Expert Opin Biol Ther. 2024 Oct;24(10):1171-1182. doi: 10.1080/14712598.2024.2400523. Epub 2024 Sep 17.

DOI:10.1080/14712598.2024.2400523
PMID:39234698
Abstract

BACKGROUND

This study evaluated physicians' and patients' beliefs about biosimilars in Hong Kong, India, Pakistan, Singapore, Taiwan, and Thailand.

RESEARCH DESIGN AND METHODS

An online survey administered to physicians (dermatologists,  = 119; gastroenterologists,  = 148; rheumatologists,  = 161) between 22 October 2021 and 7 January 2022, and patients ( = 90) with rheumatic or inflammatory bowel disease between 25 October 2021 and 12 April 2022.

RESULTS

Most (68%) physicians reported having a strong knowledge about biosimilars, yet 49% indicated that biosimilars are readily available to them. Physicians cited potential cost savings (81%) as the main benefit of biosimilars, and cost/coverage support (36%), patient support (25%), and increasing biosimilar awareness/education (24%) as main strategies for improving usage. Few (21%) patients reported having a strong knowledge about biosimilars. Patients cited offering alternatives in case of drug shortages (77%) as the main benefit of biosimilars, and cost/coverage support (53%), increasing awareness of product profile (22%), and providing biosimilars with a good efficacy profile/effective product (19%) as main strategies for improving usage.

CONCLUSION

Programs focused on cost/coverage support, patient support, and biosimilar awareness could improve acceptance of biosimilars for chronic immune-mediated inflammatory diseases in Asian countries, thereby increasing patient access to essential biologic therapies.

摘要

背景

本研究评估了香港、印度、巴基斯坦、新加坡、中国台湾和泰国的医生和患者对生物类似药的看法。

研究设计和方法

2021 年 10 月 22 日至 2022 年 1 月 7 日期间,对皮肤科医生( = 119)、胃肠病学家( = 148)和风湿病学家( = 161)进行了在线调查,同时对患有风湿或炎症性肠病的患者( = 90)进行了在线调查,调查于 2021 年 10 月 25 日至 2022 年 4 月 12 日进行。

结果

大多数(68%)医生表示对生物类似药有很强的了解,但 49%的医生表示他们很容易获得生物类似药。医生认为潜在的成本节约(81%)是生物类似药的主要益处,而成本/覆盖范围支持(36%)、患者支持(25%)和提高生物类似药的认识/教育(24%)是提高使用率的主要策略。少数(21%)患者表示对生物类似药有很强的了解。患者认为在药物短缺时提供替代药物(77%)是生物类似药的主要益处,而成本/覆盖范围支持(53%)、提高产品概况的认识(22%)、提供具有良好疗效/有效的产品(19%)是提高使用率的主要策略。

结论

专注于成本/覆盖范围支持、患者支持和生物类似药认识的计划可以提高亚洲国家对慢性免疫介导的炎症性疾病的生物类似药的接受度,从而增加患者获得基本生物治疗的机会。

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