Department of Otolaryngology-Head and Neck Surgery, University of Minnesota School of Medicine, Minneapolis, Minnesota.
Division of Speech and Hearing Sciences, Department of Health Sciences, University of North Carolina at Chapel Hill School of Medicine, 321 S Columbia Street, Chapel Hill, North Carolina, USA.
Curr Opin Otolaryngol Head Neck Surg. 2024 Dec 1;32(6):403-409. doi: 10.1097/MOO.0000000000001009. Epub 2024 Sep 4.
Otolaryngologists are vital to successfully managing chronic cough in adults. This review presents updates regarding rapidly evolving concepts in chronic cough.
Significant growth is occurring in chronic cough research, strengthening the evidence of its major psychosocial impacts. Elucidation of the neural underpinnings of normal and abnormal cough within both the peripheral and central nervous systems highlight the previously underappreciated complexity of cough. Recent clinical practice recommendations emphasize personalized treatment approaches through addressing treatable traits of chronic cough. Investigations are ongoing to better distinguish chronic cough subgroups, and multiple types of important clinical outcome measures are being characterized. Newer research about chronic cough treatment encompasses pharmacologic and nonpharmacologic interventions, including oral and inhaled medications, superior laryngeal nerve blocks, and behavioral therapy.
As knowledge about chronic cough in adults continues to expand in both research and clinical practice, otolaryngologists can continue to raise awareness of the role of the larynx in cough and promote ongoing multidisciplinary collaborations. In the coming years, more pharmacologic options and personalized treatment approaches will likely emerge for chronic cough.
耳鼻喉科医生对于成功治疗成人慢性咳嗽至关重要。本文综述了慢性咳嗽领域快速发展的相关概念。
慢性咳嗽的研究取得了显著进展，其主要的社会心理影响的证据也得到了加强。外周和中枢神经系统中正常和异常咳嗽的神经基础的阐明凸显了咳嗽以前被低估的复杂性。最近的临床实践建议强调通过治疗慢性咳嗽的可治疗特征来采用个性化的治疗方法。目前正在进行研究以更好地区分慢性咳嗽亚组，并且正在对多种重要的临床结局测量方法进行特征描述。关于慢性咳嗽治疗的新研究包括药物和非药物干预，包括口服和吸入药物、喉上神经阻滞和行为疗法。
随着在研究和临床实践中对成人慢性咳嗽的认识不断扩展，耳鼻喉科医生可以继续提高对喉部在咳嗽中的作用的认识，并促进持续的多学科合作。在未来几年中，可能会出现更多的药物治疗选择和个性化的治疗方法来治疗慢性咳嗽。
