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[白塞病:通过静脉淤滞试验和去氨加压素输注进行的血管功能研究]

[Behçet's disease: a vascular function study by the venostasis test and DDAVP infusion].

作者信息

Le Roux G, Guillevin L, Casassus P, Gayraud M, Limon S

出版信息

Rev Med Interne. 1985 Mar;6(2):111-5. doi: 10.1016/s0248-8663(85)80054-0.

Abstract

Recurrent thromboembolic accidents are frequent complications of Behçet's disease. Ten patients were investigated, 5 of them during an acute exacerbation of the disease. Abnormal responses to the venostasis test and to DDAVP (i.v.) were demonstrated in acute cases. Factor VIII activities after DDAVP were increased in all 10 patients, which suggests that the response of the vascular endothelium to the stimulus was normal and that a fibrinolytic system inhibitor may be present in the plasma of some patients.

摘要

复发性血栓栓塞事件是白塞病常见的并发症。对10例患者进行了调查,其中5例处于疾病急性加重期。在急性病例中证实了对静脉淤滞试验和去氨加压素(静脉注射)的异常反应。所有10例患者在注射去氨加压素后因子VIII活性均升高,这表明血管内皮对刺激的反应正常,且部分患者血浆中可能存在纤溶系统抑制剂。

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