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[白塞病:通过静脉淤滞试验和去氨加压素输注进行的血管功能研究]

[Behçet's disease: a vascular function study by the venostasis test and DDAVP infusion].

作者信息

Le Roux G, Guillevin L, Casassus P, Gayraud M, Limon S

出版信息

Rev Med Interne. 1985 Mar;6(2):111-5. doi: 10.1016/s0248-8663(85)80054-0.

DOI:10.1016/s0248-8663(85)80054-0
PMID:3923585
Abstract

Recurrent thromboembolic accidents are frequent complications of Behçet's disease. Ten patients were investigated, 5 of them during an acute exacerbation of the disease. Abnormal responses to the venostasis test and to DDAVP (i.v.) were demonstrated in acute cases. Factor VIII activities after DDAVP were increased in all 10 patients, which suggests that the response of the vascular endothelium to the stimulus was normal and that a fibrinolytic system inhibitor may be present in the plasma of some patients.

摘要

复发性血栓栓塞事件是白塞病常见的并发症。对10例患者进行了调查,其中5例处于疾病急性加重期。在急性病例中证实了对静脉淤滞试验和去氨加压素(静脉注射)的异常反应。所有10例患者在注射去氨加压素后因子VIII活性均升高,这表明血管内皮对刺激的反应正常,且部分患者血浆中可能存在纤溶系统抑制剂。

相似文献

1
[Behçet's disease: a vascular function study by the venostasis test and DDAVP infusion].[白塞病:通过静脉淤滞试验和去氨加压素输注进行的血管功能研究]
Rev Med Interne. 1985 Mar;6(2):111-5. doi: 10.1016/s0248-8663(85)80054-0.
2
Evidence for an endothelial cell dysfunction in association with Behçet's disease.与白塞病相关的内皮细胞功能障碍的证据。
Thromb Res. 1984 May 15;34(4):277-85. doi: 10.1016/0049-3848(84)90384-0.
3
Factor VII and fibrinolytic response to deamino-8-D-argenine vasopressin in normal subjects and dissociate response in some patients with haemophilia and von Willebrand's disease.正常受试者中因子 VII 及对去氨基-8-D-精氨酸加压素的纤溶反应,以及血友病和血管性血友病患者中的分离反应。
Br J Haematol. 1980 Jul;45(3):499-511. doi: 10.1111/j.1365-2141.1980.tb07169.x.
4
[Plasma coagulation and fibrinolysis parameters in patients with vascular Behçet's disease, and analysis of the multimeric structure of von Willebrand factor (vWF)].[血管性白塞病患者的血浆凝血和纤维蛋白溶解参数以及血管性血友病因子(vWF)多聚体结构分析]
Ryumachi. 1993 Oct;33(5):416-23.
5
Properties of the factor VIII after DDAVP (1-deamino-8-D-arginine vasopressin) infusion in normal subjects.正常受试者输注去氨加压素(1-去氨基-8-D-精氨酸加压素)后因子VIII的特性
Tohoku J Exp Med. 1980 Oct;132(2):133-40. doi: 10.1620/tjem.132.133.
6
The influence of DDAVP infusion on the coagulation and fibrinolytic response to surgery.去氨加压素输注对手术凝血和纤溶反应的影响。
Thromb Haemost. 1986 Feb 28;55(1):54-7.
7
The effect of desamino-D-arginine vasopressin (DDAVP) and naloxone infusions on factor VIII and possible endothelial cell (EC) related activities.去氨基-D-精氨酸血管加压素(DDAVP)和纳洛酮输注对凝血因子VIII及可能的内皮细胞相关活性的影响。
Br J Haematol. 1984 Aug;57(4):651-62.
8
The inability of propranolol and aspirin to inhibit the response of fibrinolytic activity and factor VIII-antigen to infusion of DDAVP.普萘洛尔和阿司匹林无法抑制纤溶活性和因子VIII抗原对去氨加压素输注的反应。
Thromb Haemost. 1984 Feb 28;51(1):42-4.
9
Impaired fibrinolytic response to DDAVP and venous occlusion in a sub-group of patients with von Willebrand's disease.
Thromb Res. 1981;23(4-5):365-74. doi: 10.1016/0049-3848(81)90197-3.
10
Venostasis but not DDAVP infusion provokes the plasma fibronectin increase.静脉郁滞而非输注去氨加压素会引起血浆纤连蛋白增加。
Thromb Haemost. 1990 Oct 22;64(2):294-6.