AIT Austrian Institute of Technology GmbH, Vienna, Austria.
Helmholtz Zentrum München, Oberschleissheim, Germany.
Microb Biotechnol. 2024 Sep;17(9):e14550. doi: 10.1111/1751-7915.14550.
In recent years, microbiomes and their potential applications for human, animal or plant health, food production and environmental management came into the spotlight of major national and international policies and strategies. This has been accompanied by substantial R&D investments in both public and private sectors, with an increasing number of products entering the market. Despite widespread agreement on the potential of microbiomes and their uses across disciplines, stakeholders and countries, there is no consensus on what defines a microbiome application. This often results in non-comprehensive communication or insufficient documentation making commercialisation and acceptance of the novel products challenging. To showcase the complexity of this issue we discuss two selected, well-established applications and propose criteria defining a microbiome application and their conditions of use for clear communication, facilitating suitable regulatory frameworks and building trust among stakeholders.
近年来，微生物组及其在人类、动物或植物健康、食品生产和环境管理方面的潜在应用成为国家和国际政策和战略的焦点。这伴随着公共和私营部门在研发方面的大量投资，越来越多的产品进入市场。尽管在微生物组及其跨学科、利益相关者和国家的应用方面存在广泛共识，但对于什么是微生物组应用并没有共识。这通常导致沟通不全面或文件记录不足，从而使新产品的商业化和接受变得具有挑战性。为了展示这个问题的复杂性，我们讨论了两个选定的、成熟的应用，并提出了定义微生物组应用的标准及其使用条件，以实现清晰的沟通，促进合适的监管框架，并在利益相关者之间建立信任。
