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颈椎间盘置换术后的足迹不匹配除了种族因素,还来自退行性因素。

The footprint mismatch of cervical disc arthroplasty comes from degenerative factor besides ethnic factor.

机构信息

Chang Gung University College of Medicine, No.259, Wenhua First Road, Guishan District, Taoyuan City, 333, Taiwan.

Bone and Joint Research Center, Linkou Chang Gung Memorial Hospital, No. 5, Fuxing Street, Guishan District, Taoyuan City, 333, Taiwan.

出版信息

Sci Rep. 2024 Sep 5;14(1):20673. doi: 10.1038/s41598-024-71786-5.

Abstract

A mismatch in footprints of cervical total disc arthroplasty (CTDA) implants occasionally occurred in Asian population and it had been attributed solely to ethnic factor. Yet, cervical degeneration process may play a role. Our purpose was to compare the cervical vertebra morphometric data with and without degeneration. The study included patients with CT scans of cervical spine from our hospital between January, 2019, and September, 2021. The total cervical degenerative index (TCDI) of each patient were collected by adding CDI score for 5 disc-levels. Patients were categorized into normal (TCDI 0-5) and degeneration groups (TCDI 6-60). Various measurements of the C3-C7 vertebral body and endplate were taken. Forty-nine patients in the normal group and 55 in the degeneration group were included. No significant difference was noted in gender, BH, BW, or BMI except age and TCDI (p < .001). During degeneration, disproportional endplate size changes were observed, with an increment ratio of 12-20% in the anteroposterior and 5-17% in the mediolateral plane throughout C3-C7, while vertebral body height remained constant. In conclusion, degeneration process, besides ethnic factor, causes the endplate size and shape mismatch. This information can help spine surgeon choose appropriate implants in CTDA surgery.

摘要

颈椎间盘全置换术(CTDA)植入物的足迹在亚洲人群中偶尔会出现不匹配的情况,这被归因于种族因素。然而,颈椎退行性变过程可能也起着一定的作用。我们的目的是比较有和无退变的颈椎椎体形态计量学数据。该研究纳入了 2019 年 1 月至 2021 年 9 月期间在我院行颈椎 CT 扫描的患者。每位患者的总颈椎退行性指数(TCDI)通过在 5 个椎间盘水平的 CDI 评分上加总得出。将患者分为正常组(TCDI 0-5)和退变组(TCDI 6-60)。对 C3-C7 椎体和终板的各种测量值进行了测量。正常组 49 例,退变组 55 例。除年龄和 TCDI(p<0.001)外,两组间的性别、体重指数(BMI)、体重(BW)或身高(BH)均无显著差异。在退变过程中,观察到终板大小的不成比例变化,前后径和左右径的增量比分别为 12-20%和 5-17%,而椎体高度保持不变。总之,除了种族因素外,退行性变过程还会导致终板大小和形状不匹配。这些信息可以帮助脊柱外科医生在 CTDA 手术中选择合适的植入物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3772/11377700/18c44d4ee360/41598_2024_71786_Fig1_HTML.jpg

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