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美国接受医疗补助的儿童在重症监护病房入院和死亡方面贫困和种族影响的多状态分析(2007-2014 年)。

A multi-state analysis on the effect of deprivation and race on PICU admission and mortality in children receiving Medicaid in United States (2007-2014).

机构信息

Institute of Child Health, University College London, London, UK.

Division of Neonatology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, USA.

出版信息

BMC Pediatr. 2024 Sep 5;24(1):565. doi: 10.1186/s12887-024-05031-3.

Abstract

INTRODUCTION

In the United States (US), racial and socioeconomic disparities have been implicated in pediatric intensive care unit (PICU) admissions and outcomes, with higher rates of critical illness in more deprived areas. The degree to which this persists despite insurance coverage is unknown. We investigated whether disparities exist in PICU admission and mortality according to socioeconomic position and race in children receiving Medicaid.

METHODS

Using Medicaid data from 2007-2014 from 23 US states, we tested the association between area level deprivation and race on PICU admission (among hospitalized children) and mortality (among PICU admissions). Race was categorized as Black, White, other and missing. Patient-level ZIP Code was used to generate a multicomponent variable describing area-level social vulnerability index (SVI). Race and SVI were simultaneously tested for associations with PICU admission and mortality.

RESULTS

The cohort contained 8,914,347 children (23·0% Black). There was no clear trend in odds of PICU admission by SVI; however, children residing in the most vulnerable quartile had increased PICU mortality (aOR 1·12 (95%CI 1·04-1·20; p = 0·0021). Black children had higher odds of PICU admission (aOR 1·04; 95% CI 1·03-1·05; p < 0·0001) and higher mortality (aOR 1·09; 95% CI 1·02-1·16; p = 0·0109) relative to White children. Substantial state-level variation was apparent, with the odds of mortality in Black children varying from 0·62 to 1·8.

CONCLUSION

In a Medicaid cohort from 2007-2014, children with greater socioeconomic vulnerability had increased odds of PICU mortality. Black children were at increased risk of PICU admission and mortality, with substantial state-level variation. Our work highlights the persistence of sociodemographic disparities in outcomes even among insured children.

摘要

简介

在美国,儿科重症监护病房(PICU)的入院和结局存在种族和社会经济差异,贫困地区的重病率更高。但在有保险的情况下,这种差异是否仍然存在尚不清楚。我们调查了在接受医疗补助(Medicaid)的儿童中,根据社会经济地位和种族,PICU 入院和死亡率是否存在差异。

方法

我们使用了来自 2007 年至 2014 年 23 个美国州的 Medicaid 数据,检验了地区贫困程度和种族与 PICU 入院(住院儿童)和死亡率(PICU 入院)之间的关系。种族分为黑人、白人、其他和缺失。患者邮政编码用于生成一个多成分变量,描述地区社会脆弱性指数(SVI)。同时测试种族和 SVI 与 PICU 入院和死亡率的关联。

结果

该队列包含 8914347 名儿童(23.0%为黑人)。SVI 与 PICU 入院率之间没有明显的趋势;然而,居住在最脆弱四分位的儿童 PICU 死亡率更高(aOR 1.12(95%CI 1.04-1.20;p=0.0021)。黑人儿童 PICU 入院的几率(aOR 1.04;95%CI 1.03-1.05;p<0.0001)和死亡率(aOR 1.09;95%CI 1.02-1.16;p=0.0109)均高于白人儿童。各州之间存在明显的差异,黑人儿童的死亡率从 0.62 到 1.8 不等。

结论

在 2007 年至 2014 年的 Medicaid 队列中,社会经济脆弱性较大的儿童 PICU 死亡率增加。黑人儿童 PICU 入院和死亡率的风险增加,各州之间存在很大差异。我们的研究结果强调了即使在有保险的儿童中,结果仍然存在社会人口统计学差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca92/11375822/d3aaca4e34ec/12887_2024_5031_Fig1_HTML.jpg

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