Department of Orthopaedic Surgery, The First Affiliated Hospital of Soochow University, 188 Shizi St, Suzhou, Jiangsu, 215006, China.
Department of Orthopaedic Surgery, Taicang Affiliated Hospital of Soochow University, Taicang, Jiangsu, China.
BMC Musculoskelet Disord. 2024 Sep 5;25(1):711. doi: 10.1186/s12891-024-07773-8.
This study aimed to evaluate the clinical effect of different vertebral body heights restoration rate after percutaneous kyphoplasty (PKP) for the treatment of osteoporotic vertebral compression fractures (OVCF).
The patients were divided into two groups according to the height restoration rate of the anterior edge of the vertebral body fracture after PKP operation using X-Ray imaging. The group A was below 80%, and the group B was above 80%. Clinical preoperative and postoperative efficacy (1st day, 1st month, 6th month, and 12th month after surgery) were evaluated according to VAS, Oswestry Disability Index(ODI), Quality of Life Questionnaire of the European Foundation for Osteoporosis(QUALEFFO), and Back Pain Life Disorder Questionnaire(RQD). Simultaneously, the preoperative and postoperative local Cobb angles and changes in the injured vertebrae in the two groups were calculated and analyzed.
The postoperative Cobb angle in group A was significantly higher than that in group B. The correction rate in group B was significantly better than that in group A. The VAS, ODI, QUALEFFO, and RQD scores of group B patients were significantly lower than those of patients in group A at each follow-up time point. The correlation coefficients of vertebral body height restoration rate and VAS, ODI, QUALEFFO, and RQD scores at the last follow-up were - 0.607 (P < 0.01), -0.625 (P < 0.01), -0.696 (P < 0.01), and - 0.662 (P < 0.01), respectively.
The results of the correlation analysis between the vertebral body height restoration rate and the above clinical efficacy scores show that increasing the vertebral body anterior height restoration rate is beneficial for pain relief and improves the clinical efficacy of patients. Simultaneously, improving the height restoration rate of the anterior edge of the vertebral body and restoring the normal spinal structure is beneficial for reducing the incidence of refracture of the adjacent vertebral body.
本研究旨在评估经皮椎体后凸成形术（PKP）治疗骨质疏松性椎体压缩性骨折（OVCF）后不同椎体高度恢复率的临床疗效。
根据 PKP 术后 X 线影像学上椎体骨折前缘高度恢复率，将患者分为两组。组 A 低于 80%，组 B 高于 80%。根据视觉模拟评分（VAS）、Oswestry 功能障碍指数（ODI）、欧洲骨质疏松症基金会生活质量问卷（QUALEFFO）和腰背疼痛生活障碍问卷（RQD），评估两组患者术前和术后 1 天、1 个月、6 个月和 12 个月的临床疗效。同时，计算和分析两组患者术前和术后局部 Cobb 角及伤椎变化。
组 A 的术后 Cobb 角明显高于组 B，组 B 的矫正率明显优于组 A。在每个随访时间点，组 B 患者的 VAS、ODI、QUALEFFO 和 RQD 评分均明显低于组 A 患者。末次随访时，椎体高度恢复率与 VAS、ODI、QUALEFFO 和 RQD 评分的相关系数分别为-0.607（P<0.01）、-0.625（P<0.01）、-0.696（P<0.01）和-0.662（P<0.01）。
椎体高度恢复率与上述临床疗效评分的相关性分析结果表明，增加椎体前缘高度恢复率有利于缓解疼痛，提高患者的临床疗效。同时，提高椎体前缘高度恢复率，恢复脊柱正常结构，有利于降低邻近椎体再骨折的发生率。
