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影响经皮球囊椎体后凸成形术成功后椎体再压缩的因素:一项回顾性分析

Factors affecting recompression of augmented vertebrae after successful percutaneous balloon kyphoplasty: a retrospective analysis.

作者信息

Niu Junjie, Zhou Haifei, Meng Qian, Shi Jinhui, Meng Bin, Yang Huilin

机构信息

Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, PR China.

Department of Clinical Radiology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, PR China.

出版信息

Acta Radiol. 2015 Nov;56(11):1380-7. doi: 10.1177/0284185114556016. Epub 2014 Nov 18.

Abstract

BACKGROUND

The instantaneously recovered stability and strength following vertebral augmentation prevent continuous micro-motion and further collapse of fractured vertebrae. Despite this, during follow-up of our patients, we observed recompression of augmented vertebrae with significant vertebral height loss and aggravation of local kyphotic deformity.

PURPOSE

To identify the risk factors related to recompression and to evaluate the clinical significance of recompression.

MATERIAL AND METHODS

One hundred and twenty-one patients who underwent single-level kyphoplasty for osteoporotic vertebral fractures were retrospectively analyzed and classified into the following two groups: group 1 with recompression and group 2 without recompression. Characteristics of patients and fractured vertebrae were compared between the two groups. Univariate and multivariate regression analyses were performed to identify risk factors for recompression. We evaluated the visual analogue scale (VAS) and the Oswestry disability index (ODI) scores in both groups to elucidate the clinical impact.

RESULTS

During an average of 20.75 ± 4.43 months of follow-up, 17 augmented vertebrae developed recompression. In the recompression group, vertebral height loss was accompanied by significantly aggravated local kyphotic deformity. The local kyphotic angle differed significantly between the two groups at final follow-up (P = 0.011). However, the VAS and ODI scores were maintained at final follow-up in both groups although the values were slightly higher in group 1. Solid lump distribution pattern (OR = 8.718; P = 0.003) and the degree of vertebral height restoration (OR = 1.260; P < 0.001) were identified as the most important risk factors for recompression.

CONCLUSION

Fractured vertebrae containing solid lump cement and those with more vertebral height restoration are at higher risk of recompression. More attention should be given to these patients considering the aggravated local kyphotic deformity.

摘要

背景

椎体强化术后即刻恢复的稳定性和强度可防止骨折椎体持续微动及进一步塌陷。尽管如此,在对我们的患者进行随访期间,我们观察到强化椎体出现再压缩,伴有显著的椎体高度丢失和局部后凸畸形加重。

目的

确定与再压缩相关的危险因素,并评估再压缩的临床意义。

材料与方法

回顾性分析121例行单节段经皮椎体后凸成形术治疗骨质疏松性椎体骨折的患者,并将其分为以下两组:1组为再压缩组,2组为无再压缩组。比较两组患者及骨折椎体的特征。进行单因素和多因素回归分析以确定再压缩的危险因素。我们评估了两组患者的视觉模拟评分(VAS)和Oswestry功能障碍指数(ODI)评分,以阐明其临床影响。

结果

在平均20.75±4.43个月的随访期间,17个强化椎体出现再压缩。在再压缩组中,椎体高度丢失伴有局部后凸畸形显著加重。末次随访时两组局部后凸角差异有统计学意义(P = 0.011)。然而,两组末次随访时VAS和ODI评分均得以维持,尽管1组的值略高。骨水泥呈实心团块状分布模式(OR = 8.718;P = 0.003)和椎体高度恢复程度(OR = 1.260;P < 0.001)被确定为再压缩的最重要危险因素。

结论

骨水泥呈实心团块状的骨折椎体以及椎体高度恢复较多的椎体再压缩风险较高。鉴于局部后凸畸形加重,应更多关注这些患者。

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