Kunitsky Abby, Maddineni Gautam, Janecki Julia, Jurkovic Edward, Ferrer Vladimir
Gastroenterology, Kansas City University, Kansas City, USA.
Internal Medicine, Florida State University College of Medicine, Cape Coral, USA.
Cureus. 2024 Aug 5;16(8):e66220. doi: 10.7759/cureus.66220. eCollection 2024 Aug.
Pure primary gastric squamous cell carcinoma (PGSCC) is a notably rare gastric malignancy. We present the case of a 51-year-old woman with advanced gastric squamous cell carcinoma characterized by a 7.6 cm necrotic mass invading the proximal stomach, liver metastasis, and lymphadenopathy at diagnosis. Despite the lack of standardized treatment protocols, we review tumor markers and potential management strategies, including surgical and chemotherapeutic interventions. The rarity and aggressive nature of PGSCC necessitates further research to develop effective detection and treatment methods to improve patient prognosis and survival outcomes.
纯原发性胃鳞状细胞癌(PGSCC)是一种极为罕见的胃部恶性肿瘤。我们报告了一例51岁女性晚期胃鳞状细胞癌病例,其特征为诊断时出现一个7.6厘米的坏死肿块,侵犯胃近端,伴有肝转移和淋巴结病。尽管缺乏标准化治疗方案,我们仍回顾了肿瘤标志物及潜在的管理策略,包括手术和化疗干预措施。PGSCC的罕见性及侵袭性需要进一步研究以开发有效的检测和治疗方法,从而改善患者的预后和生存结局。