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胃原发性鳞状细胞癌1例罕见病例报告

A Rare Case of Primary Squamous Cell Carcinoma of the Stomach: A Case Report.

作者信息

Kunitsky Abby, Maddineni Gautam, Janecki Julia, Jurkovic Edward, Ferrer Vladimir

机构信息

Gastroenterology, Kansas City University, Kansas City, USA.

Internal Medicine, Florida State University College of Medicine, Cape Coral, USA.

出版信息

Cureus. 2024 Aug 5;16(8):e66220. doi: 10.7759/cureus.66220. eCollection 2024 Aug.

DOI:10.7759/cureus.66220
PMID:39238700
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11374448/
Abstract

Pure primary gastric squamous cell carcinoma (PGSCC) is a notably rare gastric malignancy. We present the case of a 51-year-old woman with advanced gastric squamous cell carcinoma characterized by a 7.6 cm necrotic mass invading the proximal stomach, liver metastasis, and lymphadenopathy at diagnosis. Despite the lack of standardized treatment protocols, we review tumor markers and potential management strategies, including surgical and chemotherapeutic interventions. The rarity and aggressive nature of PGSCC necessitates further research to develop effective detection and treatment methods to improve patient prognosis and survival outcomes.

摘要

纯原发性胃鳞状细胞癌（PGSCC）是一种极为罕见的胃部恶性肿瘤。我们报告了一例51岁女性晚期胃鳞状细胞癌病例，其特征为诊断时出现一个7.6厘米的坏死肿块，侵犯胃近端，伴有肝转移和淋巴结病。尽管缺乏标准化治疗方案，我们仍回顾了肿瘤标志物及潜在的管理策略，包括手术和化疗干预措施。PGSCC的罕见性及侵袭性需要进一步研究以开发有效的检测和治疗方法，从而改善患者的预后和生存结局。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d46b/11374448/99904fa888cc/cureus-0016-00000066220-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d46b/11374448/9385d0876f4e/cureus-0016-00000066220-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d46b/11374448/82d0a866a40e/cureus-0016-00000066220-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d46b/11374448/99904fa888cc/cureus-0016-00000066220-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d46b/11374448/9385d0876f4e/cureus-0016-00000066220-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d46b/11374448/82d0a866a40e/cureus-0016-00000066220-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d46b/11374448/99904fa888cc/cureus-0016-00000066220-i03.jpg

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本文引用的文献

1
Gastric squamous cell carcinoma: A rare malignancy, literature review and management recommendations (Review).胃鳞状细胞癌：一种罕见的恶性肿瘤，文献综述与管理建议（综述）
Mol Clin Oncol. 2023 Aug 30;19(4):81. doi: 10.3892/mco.2023.2677. eCollection 2023 Oct.
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A type of neoplasia deadlier than gastric adenocarcinoma? Report of a case of primary gastric squamous cell carcinoma.一种比胃腺癌更致命的肿瘤？原发性胃鳞癌 1 例报告。
World J Surg Oncol. 2019 Jun 29;17(1):113. doi: 10.1186/s12957-019-1657-x.
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Gastric squamous cell carcinoma and gastric adenosquamous carcinoma, clinical features and outcomes of rare clinical entities: a National Cancer Database (NCDB) analysis.
胃鳞状细胞癌和胃腺鳞癌：罕见临床实体的临床特征与结局——一项国家癌症数据库（NCDB）分析
J Gastrointest Oncol. 2019 Feb;10(1):85-94. doi: 10.21037/jgo.2018.10.06.
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Primary Gastric Squamous Cell Carcinoma.原发性胃鳞状细胞癌
Cureus. 2018 Mar 28;10(3):e2389. doi: 10.7759/cureus.2389.
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Poorer prognosis in patients with advanced gastric squamous cell carcinoma compared with adenocarcinoma of the stomach: Case report.晚期胃鳞状细胞癌患者与胃腺癌患者相比预后较差：病例报告。
Medicine (Baltimore). 2017 Dec;96(50):e9224. doi: 10.1097/MD.0000000000009224.
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Primary Squamous Cell Carcinoma of the Stomach.原发性胃鳞状细胞癌
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Gastroenterol Res Pract. 2016;2016:3062547. doi: 10.1155/2016/3062547. Epub 2016 Jul 5.
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A Rare Case of a Primary Squamous Cell Carcinoma of the Stomach Presenting as a Submucosal Mass.一例表现为黏膜下肿块的原发性胃鳞状细胞癌罕见病例。
Case Rep Surg. 2015;2015:482342. doi: 10.1155/2015/482342. Epub 2015 Jun 21.