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心力衰竭患者的右束支传导阻滞与再次住院

Right Bundle Branch Block and Rehospitalization in Patients With Heart Failure.

作者信息

Sano Takahide, Kiuchi Shunsuke, Hisatake Shinji, Ikeda Takanori

机构信息

Division of Cardiovascular Medicine, Department of Internal Medicine, Toho University Graduate School of Medicine, Tokyo, JPN.

出版信息

Cureus. 2024 Aug 5;16(8):e66238. doi: 10.7759/cureus.66238. eCollection 2024 Aug.

Abstract

OBJECTIVE

The most important aspect of managing heart failure (HF) is preventing rehospitalization. Bundle branch block (BBB), particularly left BBB (LBBB), has been a known risk factor for worsening prognosis, whereas no such consideration has been made for right BBB (RBBB). However, recent research has shown that RBBB was associated with increased mortality. This study evaluated the effects of RBBB on prognosis, especially rehospitalization, in patients with HF.

MATERIALS

This study included 698 patients admitted for HF. Those who died in the hospital (n = 31) and dropped out during observation (n = 143) were excluded. After one year of observation, the patients were divided into a control group (n = 361) and a major adverse cardiovascular event (MACE) group (n = 163). After further excluding according to electrocardiography findings, patients were categorized as having no BBB (n = 307), pure RBBB (n = 37), and LBBB (n = 56), and then the characteristics, clinical data, and prognosis of the remaining patients were evaluated.

RESULTS

Patients were compared to no BBB, pure RBBB, and LBBB was associated with a risk for HF rehospitalization (p = 0.007). Furthermore, pure RBBB was independently associated with HF rehospitalization even after adjusting for confounders (hazard ratio: 2.40 (95% confidence interval: 1.26-4.58; p = 0.008).

CONCLUSION

Pure RBBB was independently associated with HF rehospitalization, highlighting the need for vigilance against the risk of HF rehospitalization among those with pure RBBB.

摘要

目的

管理心力衰竭(HF)最重要的方面是预防再次住院。束支传导阻滞(BBB),尤其是左束支传导阻滞(LBBB),一直是已知的预后恶化风险因素,而右束支传导阻滞(RBBB)则未被如此考虑。然而,最近的研究表明,RBBB与死亡率增加有关。本研究评估了RBBB对HF患者预后,尤其是再次住院的影响。

材料

本研究纳入了698例因HF入院的患者。排除在医院死亡(n = 31)和观察期间退出(n = 143)的患者。经过一年的观察,将患者分为对照组(n = 361)和主要不良心血管事件(MACE)组(n = 163)。根据心电图结果进一步排除后,将患者分为无BBB(n = 307)、单纯RBBB(n = 37)和LBBB(n = 56),然后评估其余患者的特征、临床数据和预后。

结果

将患者与无BBB进行比较,单纯RBBB和LBBB与HF再次住院风险相关(p = 0.007)。此外,即使在调整混杂因素后,单纯RBBB仍与HF再次住院独立相关(风险比:2.40(95%置信区间:1.26 - 4.58;p = 0.008)。

结论

单纯RBBB与HF再次住院独立相关,突出了对单纯RBBB患者HF再次住院风险保持警惕的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9740/11375113/d8488b4a24b2/cureus-0016-00000066238-i01.jpg

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Right Bundle Branch Block: Current Considerations.右束支传导阻滞:当前的考虑因素。
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