Ghewade Prajakta, Shukla Samarth, Vagha Sunita, Kalode Shivali S, Gadkari Pravin
Department of Pathology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research (Deemed to be University), Wardha, IND.
Cureus. 2024 Aug 6;16(8):e66269. doi: 10.7759/cureus.66269. eCollection 2024 Aug.
Of all primary bladder cancers, primary adenocarcinoma is an uncommon tumor. When considering all tumor origin areas, secondary bladder involvement from carcinoma, whether by direct extension or metastasis, is actually more prevalent than primary adenocarcinoma, despite its rarity. The most common source of subsequent bladder tumors is endometrial, lung, colon, prostate, breast, or other organ adenocarcinomas. Primary bladder adenocarcinoma is thought to result from urothelial metaplasia, which is frequently linked to persistent irritation or inflammation. Bladder exstrophy, recurrent urinary tract infections, long-term irritation from calculi or foreign bodies, and history of schistosomiasis are risk factors. A portion of these malignancies are associated with urachal remnants, where the tumor originates at the dome of bladder. Here we present a case of primary adenocarcinoma in a 44-year-old female patient that originated from the dome of urinary bladder.
在所有原发性膀胱癌中，原发性腺癌是一种罕见的肿瘤。当考虑所有肿瘤起源部位时，癌累及膀胱（无论是直接蔓延还是转移）实际上比原发性腺癌更为常见，尽管原发性腺癌很罕见。继发性膀胱肿瘤最常见的来源是子宫内膜、肺、结肠、前列腺、乳腺或其他器官的腺癌。原发性膀胱腺癌被认为是由尿路上皮化生引起的，这通常与持续性刺激或炎症有关。膀胱外翻、复发性尿路感染、结石或异物的长期刺激以及血吸虫病史都是危险因素。这些恶性肿瘤中有一部分与脐尿管残余有关，肿瘤起源于膀胱顶部。在此，我们报告一例44岁女性患者的原发性腺癌，该肿瘤起源于膀胱顶部。
