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成人肝母细胞瘤与乙型肝炎病毒合并感染

Adult Hepatoblastoma and Concomitant Hepatitis B Infection.

作者信息

Nieto Dominguez Alejandro, Eichinger Sarah Elizabeth, Matrova Elza, Almoghrabi Anas

机构信息

Department of Internal Medicine, John H. Stroger Jr. Hospital of Cook County, Chicago, IL.

Department of Pathology, John H. Stroger Jr. Hospital of Cook County, Chicago, IL.

出版信息

ACG Case Rep J. 2024 Sep 5;11(9):e01491. doi: 10.14309/crj.0000000000001491. eCollection 2024 Sep.

Abstract

We report a case of hepatoblastoma in a 26-year-old man with a background of type 2 diabetes mellitus and untreated hepatitis B, initially presenting with hematemesis and a recent diagnosis of hepatocellular carcinoma on computed tomography scan from a different hospital and recent referral to hospice. On presentation to our hospital, given atypical presentation for hepatocellular carcinoma, histological examination was made, revealing hepatoblastoma. Treatment included chemotherapy and management of hepatitis B, although complicated by chemotherapy-induced cytopenias and tumor progression, ultimately losing the patient to follow-up after 2 years.

摘要

我们报告一例26岁男性肝母细胞瘤病例,该患者有2型糖尿病病史且未治疗的乙型肝炎,最初表现为呕血,近期在另一家医院的计算机断层扫描中被诊断为肝细胞癌,最近转诊至临终关怀机构。在我院就诊时,鉴于肝细胞癌的非典型表现,进行了组织学检查,结果显示为肝母细胞瘤。治疗包括化疗和乙型肝炎的管理,尽管出现了化疗引起的血细胞减少和肿瘤进展等并发症,但最终在2年后失去了该患者的随访。

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