Esmealy Babak, Esmealy Leyla, Gholizadeh Leila, Nikookheslat Saeid, Sari-Sarraf Vahid
Faculty of Physical Education and Sport Sciences, University of Tabriz.
Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran.
Ann Med Surg (Lond). 2024 Aug 6;86(9):5230-5237. doi: 10.1097/MS9.0000000000002390. eCollection 2024 Sep.
Electrolyte imbalances are common in stroke patients and can significantly impact their overall health, potentially leading to severe complications and even fatal outcomes. In this study, we investigated the impact of combining multiple exercise training modalities (METM) with soymilk supplementation on serum electrolyte levels in stroke patients.
In a single-blind, four-arm randomized clinical trial, 120 stroke patients were randomly assigned to one of the following groups: (1) the METM group, (2) the soymilk group, (3) the METM plus soymilk group, and (4) the control group. Changes in serum electrolyte levels were compared both within and across groups over four consecutive weeks.
Upon admission, 38.3% of the participants presented with hyponatremia, 26.7% hypokalemia, and 73.3% hypocalcemia. Over time, there was an overall improvement in serum electrolyte imbalances across all study groups compared to the baseline. Between-group comparisons revealed that the METM plus soymilk group exhibited statistically significant improvements compared to the other groups with absolute reductions in the proportion of participants with hyponatremia, hypokalemia, and hypocalcemia by 43.3%, 33.3%, and 73.4%, respectively.
The study findings substantiate the common occurrence of hyponatremia, hypokalemia, and hypocalcemia during the acute phase of stroke. Implementation of the METM alongside soymilk intake demonstrated potential in rectifying electrolyte imbalances among stroke patients, hinting at a promising intervention strategy.
电解质失衡在中风患者中很常见，会显著影响他们的整体健康，可能导致严重并发症甚至致命后果。在本研究中，我们调查了多种运动训练方式（METM）与补充豆浆对中风患者血清电解质水平的影响。
在一项单盲、四臂随机临床试验中，120名中风患者被随机分配到以下组之一：（1）METM组，（2）豆浆组，（3）METM加豆浆组，以及（4）对照组。连续四周比较组内和组间血清电解质水平的变化。
入院时，38.3%的参与者出现低钠血症，26.7%出现低钾血症，73.3%出现低钙血症。随着时间推移，与基线相比，所有研究组的血清电解质失衡总体上有所改善。组间比较显示，与其他组相比，METM加豆浆组有统计学意义的改善，低钠血症、低钾血症和低钙血症参与者比例的绝对降低分别为43.3%、33.3%和73.4%。
研究结果证实了中风急性期低钠血症、低钾血症和低钙血症的普遍存在。实施METM并摄入豆浆显示出纠正中风患者电解质失衡的潜力，暗示了一种有前景的干预策略。
