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病毒学家致真菌学家的问候:一篇概述寄生于真菌中的病毒的综述。

Greetings from virologists to mycologists: A review outlining viruses that live in fungi.

作者信息

Urayama Syun-Ichi, Zhao Yan-Jie, Kuroki Misa, Chiba Yuto, Ninomiya Akihiro, Hagiwara Daisuke

机构信息

a Department of Life and Environmental Sciences, Laboratory of Fungal Interaction and Molecular Biology (donated by IFO), University of Tsukuba.

b Microbiology Research Center for Sustainability (MiCS), University of Tsukuba.

出版信息

Mycoscience. 2024 Jan 31;65(1):1-11. doi: 10.47371/mycosci.2023.11.004. eCollection 2024.

Abstract

Viruses are genetic elements that parasitize self-replicating cells. Therefore, organisms parasitized by viruses are not limited to animals and plants but also include microorganisms. Among these, viruses that parasitize fungi are known as mycoviruses. Mycoviruses with an RNA genome persistently replicate inside fungal cells and coevolve with their host cells, similar to a cellular organelle. Within host cells, mycoviruses can modulate various fungal characteristics and activities, including pathogenicity and the production of enzymes and secondary metabolites. In this review, we provide an overview of the mycovirus research field as introduction to fungal researchers. Recognition of all genetic elements in fungi aids towards better understanding and control of fungi, and makes fungi a significant model system for studying microorganisms containing multiple genetic elements.

摘要

病毒是寄生于自我复制细胞的遗传元件。因此,被病毒寄生的生物体不仅限于动物和植物,还包括微生物。其中,寄生于真菌的病毒被称为真菌病毒。具有RNA基因组的真菌病毒在真菌细胞内持续复制,并与宿主细胞共同进化,类似于细胞器。在宿主细胞内,真菌病毒可以调节各种真菌特性和活动,包括致病性以及酶和次生代谢产物的产生。在这篇综述中,我们向真菌研究人员介绍真菌病毒研究领域的概况。识别真菌中的所有遗传元件有助于更好地理解和控制真菌,并使真菌成为研究含有多种遗传元件的微生物的重要模型系统。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dc1/11371549/f46a7e835417/MYC-65-1-g01.jpg

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