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患者安全实情调查员:抗凝剂与抗血小板药物及颈椎内侧支手术

Factfinders for patient safety: Anticoagulant and antiplatelet agents and cervical medial branch procedures.

作者信息

Lee Haewon, Saffarian Mathew, Babaria Vivek, McCormick Zachary L

机构信息

University of California, San Diego, USA.

Department of Orthopedic Surgery, San Diego, CA, USA.

出版信息

Interv Pain Med. 2022 May 6;1(2):100090. doi: 10.1016/j.inpm.2022.100090. eCollection 2022 Jun.

DOI:10.1016/j.inpm.2022.100090
PMID:39239367
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11372878/
Abstract

This series of FactFinders presents a brief summary of the evidence and outlines recommendations regarding the safety of anticoagulant and antiplatelet agents for cervical medial branch blocks and cervical medial branch radiofrequency neurotomy. The evidence in support of the following facts is presented: (1) In patients maintained on therapeutic anticoagulant (AC) and/or antiplatelet (AP) therapy, for whom cervical medial branch blocks (CMBBs) are being considered, there is strong evidence to guide decisions on continuing or discontinuing these AC/AP agents in preparation for the procedure. (2) Therapeutic anticoagulation (AC) and antiplatelet (APT) agents should be discontinued prior to cervical medial branch radiofrequency neurotomy (CMBRFN) due to serious hemorrhagic risks.

摘要

本系列《事实发现者》简要总结了证据,并概述了关于抗凝剂和抗血小板药物用于颈椎内侧支阻滞及颈椎内侧支射频神经切断术安全性的建议。以下是支持这些事实的证据:(1)对于正在接受治疗性抗凝(AC)和/或抗血小板(AP)治疗且考虑进行颈椎内侧支阻滞(CMBB)的患者,有充分证据可指导在术前决定继续或停用这些AC/AP药物。(2)由于存在严重出血风险,在进行颈椎内侧支射频神经切断术(CMBRFN)之前应停用治疗性抗凝(AC)和抗血小板(APT)药物。

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本文引用的文献

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Pain Med. 2020 May 1;21(5):910-917. doi: 10.1093/pm/pnaa009.
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Update of a Study of Not Ceasing Anticoagulants for Patients Undergoing Injection Procedures for Spinal Pain.一项关于脊髓疼痛注射治疗患者不停用抗凝剂的研究的更新
Pain Med. 2020 May 1;21(5):918-921. doi: 10.1093/pm/pnz354.
3
Continuation versus discontinuation of antiplatelet therapy for bleeding and ischaemic events in adults undergoing non-cardiac surgery.非心脏手术成年患者抗血小板治疗的继续与停用对出血和缺血事件的影响
Cochrane Database Syst Rev. 2018 Jul 18;7(7):CD012584. doi: 10.1002/14651858.CD012584.pub2.
4
Anatomical Variations of the Vertebral Artery in the Upper Cervical Spine: Clinical Relevance for Procedures Targeting the C1/C2 and C2/C3 Joints.颈椎上段椎动脉解剖变异:针对 C1/C2 和 C2/C3 关节的操作的临床相关性。
Reg Anesth Pain Med. 2018 May;43(4):367-371. doi: 10.1097/AAP.0000000000000734.
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Interventional Spine and Pain Procedures in Patients on Antiplatelet and Anticoagulant Medications (Second Edition): Guidelines From the American Society of Regional Anesthesia and Pain Medicine, the European Society of Regional Anaesthesia and Pain Therapy, the American Academy of Pain Medicine, the International Neuromodulation Society, the North American Neuromodulation Society, and the World Institute of Pain.介入脊柱和疼痛程序在服用抗血小板和抗凝药物的患者中(第二版):美国区域麻醉和疼痛医学学会、欧洲区域麻醉和疼痛治疗学会、美国疼痛医学学院、国际神经调节学会、北美神经调节学会和世界疼痛学会的指南。
Reg Anesth Pain Med. 2018 Apr;43(3):225-262. doi: 10.1097/AAP.0000000000000700.
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Risks and Benefits of Ceasing or Continuing Anticoagulant Medication for Image-Guided Procedures for Spine Pain: A Systematic Review.停止或继续抗凝药物用于脊柱疼痛的影像引导操作的风险和益处:系统评价。
Pain Med. 2018 Mar 1;19(3):438-448. doi: 10.1093/pm/pnx152.
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Continuing Anti-thrombotic Medication During Low-to-Intermediate Risk Spinal Procedures: A Retrospective Evaluation.在低至中度风险脊柱手术期间继续使用抗血栓药物:回顾性评估。
Pain Physician. 2017 Jul;20(5):437-443.
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Anticoagulant and Antiplatelet Management for Spinal Procedures: A Prospective, Descriptive Study and Interpretation of Guidelines.脊柱手术的抗凝和抗血小板管理:前瞻性描述性研究与指南解读。
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Pain Med. 2017 Mar 1;18(3):403-409. doi: 10.1093/pm/pnw108.