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患者安全事实调查员:抗栓药物与介入性疼痛治疗——腰椎经椎间孔硬膜外类固醇注射和腰椎内侧支射频神经切断术

FactFinders for patient safety: Antithrombotics and interventional pain procedures -- lumbar transforaminal epidural steroid injections and lumbar medial branch radiofrequency neurotomy.

作者信息

Smith Clark, Miller David C, Saffarian Mathew, McCormick Zachary L

机构信息

Columbia University Medical Center, Rehabilitation and Regenerative Medicine, New York, NY, USA.

Napa Pain Institute, Napa, CA, USA.

出版信息

Interv Pain Med. 2021 Dec 28;1(1):100008. doi: 10.1016/j.inpm.2021.100008. eCollection 2022 Mar.

Abstract

This series of FactFinders presents a brief summary of the evidence and outlines recommendations regarding the safety of antithrombotics and two interventional pain procedures - lumbar transforaminal epidural steroid injections and lumbar medial branch radiofrequency neurotomy. The evidence in support of the following facts is presented: (1) The decision to withhold antiplatelet therapy prior to lumbar transforaminal epidural steroid injections should be made on a case-by-case basis, weighing the relative risk of hemorrhage versus the risk of thrombosis for each patient. (2) A clinically significant hemorrhagic complication has never been reported in the medical literature in association with a lumbar medial branch radiofrequency neurotomy procedure. (3) Discontinuing antithrombotics for lumbar radiofrequency neurotomy procedures, even for a short period of time, may lead to an increased incidence of cardiovascular and cerebrovascular events.

摘要

本系列《事实发现者》简要总结了相关证据,并概述了关于抗栓药物安全性以及两种介入性疼痛治疗方法——腰椎经椎间孔硬膜外类固醇注射和腰椎内侧支射频神经切断术的建议。以下是所提供的支持以下事实的证据:(1)对于腰椎经椎间孔硬膜外类固醇注射前是否停用抗血小板治疗,应根据具体情况,权衡每位患者出血相对风险与血栓形成风险后做出决定。(2)医学文献中从未报道过与腰椎内侧支射频神经切断术相关的具有临床意义的出血并发症。(3)即使在短时间内停用抗栓药物进行腰椎射频神经切断术,也可能导致心血管和脑血管事件发生率增加。

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