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含酒精漱口水与口腔癌风险:探究两者关联

Alcohol-Containing Mouthwash and the Risk of Oral Cancer: Exploring the Association.

作者信息

Rao Karthik Nagaraja, Mehta Rupa, Dange Prajwal, Nagarkar Nitin M

机构信息

Department of Head and Neck Oncology, Sri Shankara Cancer Hospital and Research Center, Bangalore, India.

Department of Otorhinolaryngology and Head Neck Surgery, All India Institute of Medical Sciences, Raipur, India.

出版信息

Indian J Surg Oncol. 2024 Sep;15(3):553-556. doi: 10.1007/s13193-024-01948-4. Epub 2024 May 8.

Abstract

Oral cavity and larynx cancers are generally associated with tobacco consumption, alcohol abuse or both. Mouthwashes are liquid antiseptic solutions that decrease the microbial load in the oral cavity. Alcohol is often used in mouthwashes for its antiseptic functions and as a carrier for some active ingredients, including menthol or thymol, helping them penetrate the plaque. There is some evidence for alcohol-containing mouthwash use which is associated with the potential risk of developing carcinoma of oral cavity. The results are inconclusive, as actual mouthwash use patterns may be inconsistent and cannot be easily quantified. Based on the available data, there is no sufficient evidence to accept the proposition that the use of mouthwashes containing alcohol can influence the development of oral cancer.

摘要

口腔癌和喉癌通常与吸烟、酗酒或两者都有关。漱口水是一种液体抗菌溶液,可减少口腔中的微生物数量。酒精常用于漱口水,因其具有抗菌功能,并作为薄荷醇或百里酚等一些活性成分的载体,帮助它们穿透牙菌斑。有一些证据表明,使用含酒精漱口水与患口腔癌的潜在风险有关。结果尚无定论,因为实际的漱口水使用模式可能不一致,且难以轻易量化。根据现有数据,没有足够的证据支持使用含酒精漱口水会影响口腔癌发生这一观点。

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