Bisht Pushpa, Khan Sabina, Mohroo Rubeena, Khetrapal Shaan, Jetley Sujata
Department of Pathology, Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi, 110062 India.
Indian J Surg Oncol. 2024 Sep;15(3):509-512. doi: 10.1007/s13193-024-01939-5. Epub 2024 Apr 19.
Ectopic thyroid tissue is defined as thyroid tissue that is present at a location other than its normal anatomical location. It can have any pathological condition that could impact the orthotopic thyroid gland. However, ectopic thyroid tissue seldom becomes malignant, and the occurrence of a follicular variant of papillary carcinoma in ectopic thyroid is much more unusual. We report a rare case of ectopic follicular variant of papillary carcinoma in a 73-year-old female with a normal orthotopic thyroid gland. Despite a few reports on ectopic papillary carcinoma thyroid (PTC) in submental, thyroglossal duct cysts, and bronchial cleft cysts with normal pathologic examinations of orthotopic thyroid, only one case of PTC in the anterior neck region without any neoplastic involvement of the orthotopic thyroid gland has been reported. Ectopic thyroid carcinoma should be taken into account in the differential diagnosis of a mass lesion in the front of the neck even in the presence of a normal thyroid gland which will aid in early diagnosis and treatment of such cases.
异位甲状腺组织被定义为存在于其正常解剖位置以外的甲状腺组织。它可能具有任何会影响原位甲状腺的病理状况。然而,异位甲状腺组织很少发生恶变,并且异位甲状腺中乳头状癌滤泡变体的发生更为罕见。我们报告了一例73岁女性的罕见病例,其原位甲状腺正常,但发生了异位乳头状癌滤泡变体。尽管有一些关于颏下、甲状舌管囊肿和支气管裂囊肿中异位乳头状甲状腺癌(PTC)的报道,且原位甲状腺病理检查正常,但仅有一例报道了前颈部区域的PTC,而原位甲状腺未发生任何肿瘤累及。即使存在正常甲状腺,在颈部前方肿块病变的鉴别诊断中也应考虑异位甲状腺癌,这将有助于此类病例的早期诊断和治疗。