Yadav Gitanjali, Yadav Sangeeta, Tomar Ravi
Department of Chemistry, Indira Gandhi University, Meerpur, Rewari, Haryana, 122502, India.
Department of Chemistry, Baba Mastnath University Asthal bohar, Rohtak, Haryana, 124021, India.
Mol Divers. 2025 Jun;29(3):2783-2797. doi: 10.1007/s11030-024-10978-7. Epub 2024 Sep 6.
Arborisidine and Arbornamine are two monoterpenoid indole alkaloids that were isolated from the Malayan Kopsia arborea plant. This review provides valuable information about the total and formal syntheses of these alkaloids. The synthesis strategies discussed in this review, such as Pictet-Spengler cyclization, chemo- and stereoselective oxidative cyclization, Michael/Mannich cascade process, and intramolecular N-alkylation, can be useful for developing new methods to synthesize these and other similar compounds.
阿波瑞西定和阿波那明是从马来亚柯蒲木植物中分离得到的两种单萜吲哚生物碱。本综述提供了有关这些生物碱全合成和形式合成的有价值信息。本综述中讨论的合成策略，如皮克特-施彭格勒环化反应、化学和立体选择性氧化环化反应、迈克尔/曼尼希级联反应以及分子内N-烷基化反应，可用于开发合成这些及其他类似化合物的新方法。
