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Dexamethasone suppression test as a simple measure of stress?地塞米松抑制试验能否作为一种简单的应激指标?
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2
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引用本文的文献

1
Increased plasma levels of circulating cell-free mitochondrial DNA in suicide attempters: associations with HPA-axis hyperactivity.自杀未遂者血浆中循环游离线粒体DNA水平升高:与下丘脑-垂体-肾上腺(HPA)轴功能亢进的关联
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Anti-purkinje cell and natural autoantibodies in a group of psychiatric patients. Evidences for a correlation with the psychopathological status.一组精神科患者中的抗浦肯野细胞抗体和天然自身抗体。与精神病理状态相关性的证据。
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3
Does the dexamethasone suppression test reliably discriminate between psychotic and nonpsychotic major depression?: an exploratory analysis of potential confounds.地塞米松抑制试验能否可靠地区分精神病性与非精神病性重度抑郁症?:对潜在混杂因素的探索性分析。
J Nerv Ment Dis. 2009 Jun;197(6):395-400. doi: 10.1097/NMD.0b013e3181a775cf.
4
[Factors interfering with the dexamethasone suppression test].
Klin Wochenschr. 1986 Jun 16;64(12):535-9. doi: 10.1007/BF01735315.
5
The dexamethasone suppression test as a variable in clinical diagnosis and research: a review.地塞米松抑制试验作为临床诊断和研究中的一个变量:综述
J R Soc Med. 1988 Jan;81(1):31-3. doi: 10.1177/014107688808100114.

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Personality and psychological stress.个性与心理压力。
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Relationship between weight gain and hypothalamic pituitary adrenal function in patients with anorexia nervosa.神经性厌食症患者体重增加与下丘脑-垂体-肾上腺功能之间的关系。
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Dexamethasone suppression testing of alcoholics.酗酒者的地塞米松抑制试验
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The dexamethasone suppression test for melancholia.
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Panic attacks and the dexamethasone suppression test.惊恐发作与地塞米松抑制试验
Am J Psychiatry. 1983 Aug;140(8):1063-4. doi: 10.1176/ajp.140.8.1063.
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The dexamethasone suppression test in suicidal patients with unipolar depression.单相抑郁症自杀患者的地塞米松抑制试验
Am J Psychiatry. 1983 Jul;140(7):877-9. doi: 10.1176/ajp.140.7.877.
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Major depression in the elderly: DSM-III criteria and the dexamethasone suppression test as predictors of treatment response.老年人的重度抑郁症:《精神疾病诊断与统计手册》第三版标准及地塞米松抑制试验作为治疗反应的预测指标
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Effects of weight loss on the dexamethasone suppression test.体重减轻对地塞米松抑制试验的影响。
Am J Psychiatry. 1983 Mar;140(3):338-41. doi: 10.1176/ajp.140.3.338.
9
Mean 14.00-17.00 h plasma cortisol concentration and its relationship to the 1 mg-dexamethasone suppression response in depressives and controls.抑郁症患者和对照组在14.00 - 17.00时的平均血浆皮质醇浓度及其与1毫克地塞米松抑制反应的关系。
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10
The clinical utility of the dexamethasone suppression test in psychiatry. Summary of a National Institute of Mental Health workshop.地塞米松抑制试验在精神病学中的临床应用。美国国立精神卫生研究所研讨会综述
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地塞米松抑制试验能否作为一种简单的应激指标?

Dexamethasone suppression test as a simple measure of stress?

作者信息

Mellsop G W, Hutton J D, Delahunt J W

出版信息

Br Med J (Clin Res Ed). 1985 Jun 15;290(6484):1804-6. doi: 10.1136/bmj.290.6484.1804.

DOI:10.1136/bmj.290.6484.1804
PMID:3924265
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1415944/
Abstract

Non-suppression of cortisol by dexamethasone has been described as a biological marker of a diagnostic subgroup of depressed patients. This paper presents the hypothesis that the degree of non-suppression is a variable that reflects the quantity of stress or distress experienced by the patient rather than relating to a specific diagnosis. Such a quantitative measure of stress would be valuable for research in general medicine as well as in psychiatry. Testing of this postulate should apply a more precise interpretation of endocrine principles than has been applied to the dexamethasone suppression test to date.

摘要

地塞米松不能抑制皮质醇已被描述为抑郁症患者一个诊断亚组的生物学标志物。本文提出一个假说,即不抑制程度是一个变量,它反映患者所经历的压力或痛苦的量,而非与特定诊断相关。这样一种压力的定量测量对于普通医学以及精神病学的研究都将是有价值的。对这一假设的检验应该比迄今为止应用于地塞米松抑制试验的内分泌学原理有更精确的解释。