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体重减轻对地塞米松抑制试验的影响。

Effects of weight loss on the dexamethasone suppression test.

作者信息

Edelstein C K, Roy-Byrne P, Fawzy F I, Dornfeld L

出版信息

Am J Psychiatry. 1983 Mar;140(3):338-41. doi: 10.1176/ajp.140.3.338.

DOI:10.1176/ajp.140.3.338
PMID:6829806
Abstract

The authors studied postdexamethasone cortisol secretion in 18 depression-free, healthy, obese subjects before and after weight loss. Although all subjects suppressed cortisol normally before weight loss, 5 of 18 (27.5%) failed to suppress cortisol after an average loss of 13.5 kg. This failure to suppress cortisol was not associated with any change in depression ratings.

摘要

作者研究了18名无抑郁、健康的肥胖受试者在减肥前后地塞米松后的皮质醇分泌情况。尽管所有受试者在减肥前皮质醇分泌均正常抑制,但18名受试者中有5名(27.5%)在平均减重13.5千克后未能抑制皮质醇分泌。这种皮质醇抑制失败与抑郁评分的任何变化均无关。

相似文献

1
Effects of weight loss on the dexamethasone suppression test.体重减轻对地塞米松抑制试验的影响。
Am J Psychiatry. 1983 Mar;140(3):338-41. doi: 10.1176/ajp.140.3.338.
2
The dexamethasone suppression test in adolescent psychiatric patients.青少年精神病患者的地塞米松抑制试验
Am J Psychiatry. 1984 Mar;141(3):421-3. doi: 10.1176/ajp.141.3.421.
3
The dexamethasone suppression test and depressive symptoms in early and late withdrawal from alcohol.酒精戒断早期和晚期的地塞米松抑制试验与抑郁症状
Am J Psychiatry. 1984 Nov;141(11):1445-8. doi: 10.1176/ajp.141.11.1445.
4
Age and the dexamethasone suppression test in depression.年龄与抑郁症中的地塞米松抑制试验
Am J Psychiatry. 1984 Jul;141(7):872-4. doi: 10.1176/ajp.141.7.872.
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[Value of the dexamethasone suppression test in anorexia nervosa].
Monatsschr Kinderheilkd. 1987 Nov;135(11):758-62.
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The dexamethasone suppression test in residual schizophrenia with depression.
Am J Psychiatry. 1984 Feb;141(2):250-2. doi: 10.1176/ajp.141.2.250.
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The dexamethasone suppression test in hospitalized prepubertal depressed children.住院青春期前抑郁儿童的地塞米松抑制试验
Am J Psychiatry. 1984 Feb;141(2):290-1. doi: 10.1176/ajp.141.2.290.
8
Influence of age and relative weight on cortisol suppression in normal subjects.年龄和相对体重对正常受试者皮质醇抑制的影响。
Am J Psychiatry. 1987 May;144(5):646-9. doi: 10.1176/ajp.144.5.646.
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Dexamethasone suppression in dementia, depression, and normal aging.痴呆、抑郁和正常衰老中的地塞米松抑制。
Am J Psychiatry. 1986 Apr;143(4):452-6. doi: 10.1176/ajp.143.4.452.
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A comparison of the cortisol suppression index and the dexamethasone suppression test.皮质醇抑制指数与地塞米松抑制试验的比较
J Clin Psychiatry. 1984 Oct;45(10):431-2.

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Low calorie dieting increases cortisol.低卡路里饮食会增加皮质醇。
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5
Carbamazepine and false positive dexamethasone suppression tests for Cushing's syndrome.卡马西平与库欣综合征的地塞米松抑制试验假阳性
BMJ. 2005 Feb 5;330(7486):299-300. doi: 10.1136/bmj.330.7486.299.
6
Abdominal obesity increases overnight cortisol excretion.腹部肥胖会增加夜间皮质醇排泄量。
J Endocrinol Invest. 1999 Jun;22(6):465-71. doi: 10.1007/BF03343591.
7
[Dexamethasone suppression test: a biologic marker of endogenous depression?].
Eur Arch Psychiatry Neurol Sci. 1984;234(2):137-46. doi: 10.1007/BF00381220.
8
[Dexamethasone suppression test in anorexia nervosa].
Eur Arch Psychiatry Neurol Sci. 1985;234(5):335-40. doi: 10.1007/BF00381045.
9
Dexamethasone suppression test as a simple measure of stress?地塞米松抑制试验能否作为一种简单的应激指标?
Br Med J (Clin Res Ed). 1985 Jun 15;290(6484):1804-6. doi: 10.1136/bmj.290.6484.1804.
10
[Factors interfering with the dexamethasone suppression test].
Klin Wochenschr. 1986 Jun 16;64(12):535-9. doi: 10.1007/BF01735315.