Edelstein C K, Roy-Byrne P, Fawzy F I, Dornfeld L
Am J Psychiatry. 1983 Mar;140(3):338-41. doi: 10.1176/ajp.140.3.338.
The authors studied postdexamethasone cortisol secretion in 18 depression-free, healthy, obese subjects before and after weight loss. Although all subjects suppressed cortisol normally before weight loss, 5 of 18 (27.5%) failed to suppress cortisol after an average loss of 13.5 kg. This failure to suppress cortisol was not associated with any change in depression ratings.
作者研究了18名无抑郁、健康的肥胖受试者在减肥前后地塞米松后的皮质醇分泌情况。尽管所有受试者在减肥前皮质醇分泌均正常抑制,但18名受试者中有5名(27.5%)在平均减重13.5千克后未能抑制皮质醇分泌。这种皮质醇抑制失败与抑郁评分的任何变化均无关。