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训练有素和未经训练的健康年轻男性的血管内皮功能及其对中等强度有氧运动的反应。

Vascular endothelial function and its response to moderate-intensity aerobic exercise in trained and untrained healthy young men.

机构信息

School of Medicine, Shaoxing University, Shaoxing, China.

College of Physical Education and Health Sciences, Zhejiang Normal University, Jinhua, China.

出版信息

Sci Rep. 2024 Sep 3;14(1):20450. doi: 10.1038/s41598-024-71471-7.

DOI:10.1038/s41598-024-71471-7
PMID:39242762
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11379850/
Abstract

30 min of moderate-intensity aerobic exercise per day is recommended, but the response and adaptation of endothelial function (EF) to this exercise remains controversial. The purpose of this study was to determine the changes in EF in endurance trained and untrained individuals before and after this exercise and to compare the differences between trained and untrained individuals. Twelve endurance-trained male college athletes (trained group) and 12 untrained male college students (untrained group) performed a 30-min run at an intensity of 60% VOmax. Brachial artery flow-mediated dilation (FMD) was measured before exercise, 30 min and 60 min after exercise, and the following morning. Resting diameter and maximum diameter showed large time effects (p < 0.001, η = 0.533; p < 0.001, η = 0.502). Resting diameters at 30 and 60 min after exercise were higher than before exercise in both the untrained and trained groups (p < 0.05), and maximum diameters at 30 min after exercise were higher than before exercise in both the untrained and trained groups (p < 0.01). Resting diameter and maximum diameter also exhibited some group effects (p = 0.055, η = 0.157; p = 0.041, η = 0.176). Resting diameters and maximum diameters were higher in the trained group than in the untrained group before exercise (p < 0.05). FMD (%) showed no time, group, or time-group interaction effects. 30 min of moderate-intensity aerobic exercise can increase resting and maximal arterial diameters in both trained and untrained young men, but has no effect on FMD. Long-term endurance training has the potential to increase resting and maximal arterial diameters in young men, but not necessarily FMD.

摘要

每天进行 30 分钟中等强度的有氧运动是被推荐的,但这种运动对内皮功能(EF)的反应和适应仍然存在争议。本研究的目的是确定在进行这种运动之前和之后,经过耐力训练的个体和未经训练的个体的 EF 变化,并比较训练和未经训练个体之间的差异。12 名耐力训练的男性大学生运动员(训练组)和 12 名未经训练的男性大学生(未训练组)以 60%VOmax 的强度进行了 30 分钟的跑步。在运动前、运动后 30 分钟和 60 分钟以及第二天早上测量肱动脉血流介导的扩张(FMD)。静息直径和最大直径显示出较大的时间效应(p<0.001,η=0.533;p<0.001,η=0.502)。未训练组和训练组在运动后 30 分钟和 60 分钟的静息直径均高于运动前(p<0.05),且未训练组和训练组在运动后 30 分钟的最大直径均高于运动前(p<0.01)。静息直径和最大直径也表现出一些组间效应(p=0.055,η=0.157;p=0.041,η=0.176)。在运动前,训练组的静息直径和最大直径均高于未训练组(p<0.05)。FMD(%)无时间、组间或时间-组间交互作用效应。30 分钟的中等强度有氧运动可以增加训练和未经训练的年轻男性的静息和最大动脉直径,但对 FMD 没有影响。长期耐力训练有可能增加年轻男性的静息和最大动脉直径,但不一定能增加 FMD。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9009/11379850/808ce7e831f6/41598_2024_71471_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9009/11379850/808ce7e831f6/41598_2024_71471_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9009/11379850/808ce7e831f6/41598_2024_71471_Fig1_HTML.jpg

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Endothelial Dysfunction in Diabetes Mellitus: New Insights.糖尿病中的血管内皮功能障碍:新的认识。
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Matrix stiffness, endothelial dysfunction and atherosclerosis.基质硬度、内皮功能障碍与动脉粥样硬化。
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