Jinan Preschool Education College, Jinan City, Shandong Province, 250307, China.
Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Traditional Chinese Medicine department, 238 Jingshi East Roa, Lixia District, Jinan City, Shandong Province, 250014, China.
BMC Psychiatry. 2024 Sep 6;24(1):604. doi: 10.1186/s12888-024-06046-x.
To assess the effectiveness of Internet-based self-help interventions in treating depression in adolescents and young adults.
A systematic search was conducted across six databases, including PubMed, to identify randomized controlled trials (RCTs) that satisfied the specified inclusion and exclusion criteria. The intervention measure consisted of Internet-based self-help interventions.
A total of 23 randomized controlled trials (RCTs) were included in this analysis. Meta-analysis indicated that Internet-based self-help therapies significantly reduced depression scores in adolescents and young adults. (OR = -0.68, 95%CI [-0.88, -0.47], P < 0.001). We examined the effects of patient recruitment from various regions, medication usage, therapist involvement, weekly intervention time, and intervention duration. Patients selected from school, primary healthcare centers, clinics and local communities had better results. Intervention lasting 30 to 60 min and 60 to180 minutes per week were effective in the short term.
The internet-based self-help intervention can be effective in treating depression in adolescents and young adults. However, factors such as patient recruitment locations, medication usage, Therapists' involvement, weekly intervention time, and intervention duration interacted with the outcome. Subgroup analysis on potential adverse effects and gender was impossible due to insufficient data from the included studies.
评估基于互联网的自助干预措施治疗青少年和年轻成年人抑郁症的效果。
在六个数据库（包括 PubMed）中进行了系统检索，以确定符合特定纳入和排除标准的随机对照试验（RCT）。干预措施包括基于互联网的自助干预。
共纳入 23 项随机对照试验（RCT）。Meta 分析表明，基于互联网的自助疗法可显著降低青少年和年轻成年人的抑郁评分。（OR = -0.68，95%CI [-0.88，-0.47]，P < 0.001）。我们研究了患者来自不同地区的招募、用药、治疗师参与、每周干预时间和干预持续时间的影响。从学校、初级保健中心、诊所和当地社区招募的患者效果更好。持续 30 至 60 分钟和每周 60 至 180 分钟的干预在短期内有效。
基于互联网的自助干预可以有效治疗青少年和年轻成年人的抑郁症。然而，患者招募地点、用药、治疗师参与、每周干预时间和干预持续时间等因素与结果相互作用。由于纳入研究的数据不足，无法对潜在的不良反应和性别进行亚组分析。
