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探讨焦虑和抑郁对急性心肌梗死患者药物治疗依从性的影响。

Examining the influence of anxiety and depression on medication adherence among patients diagnosed with acute myocardial infarction.

机构信息

Faculty of Nursing, Applied Science Private University, Amman, Jordan.

Community and Mental Health Nursing Department, Faculty of Nursing, The Hashemite University, Zarqa, Jordan.

出版信息

BMC Psychol. 2024 Sep 6;12(1):473. doi: 10.1186/s40359-024-01959-4.

Abstract

BACKGROUND

Effective medication adherence is vital for managing acute myocardial infarction (AMI) and enhancing patient well-being. This study aimed to evaluate medication adherence levels and associated factors among AMI patients using standardized assessment tools.

METHODS

Employing a cross-sectional descriptive design, the study involved 210 patients diagnosed with acute myocardial infarction. Participants completed the General Medication Adherence Scale (GMAS), Hospital Anxiety and Depression Scale (HADS), and provided socio-demographic details.

RESULTS

The study revealed partial adherence to medications among AMI patients, with mean scores of 24.89 (± 3.64) out of 33. Notably, good adherence was observed in non-adherence due to patient behavior (mean ± SD = 11.8 ± 2.3 out of 15) and additional disease burden (mean ± SD = 8.65 ± 2.21 out of 12), while partial adherence was noted in non-adherence due to financial constraints (mean ± SD = 4.44 ± 1.34 out of 6). Patients reported mild anxiety (mean ± SD = 8.38 ± 2.81) and no depressive symptoms (mean ± SD = 7.43 ± 2.42). Multiple linear regression analysis indicated that employed status, younger age, shorter duration of MI, lower anxiety, and depression levels were associated with higher medication adherence. However, factors such as monthly income, gender, educational level, and marital status did not predict medication adherence.

CONCLUSION

The study highlights the significance of addressing anxiety and depression levels and considering socio-demographic factors when designing interventions to enhance medication adherence among AMI patients. Further research is needed to explore additional determinants of medication adherence and develop tailored interventions to improve patient outcomes post-AMI.

摘要

背景

有效的药物依从性对于急性心肌梗死(AMI)的管理和提高患者的健康水平至关重要。本研究旨在使用标准化评估工具评估 AMI 患者的药物依从水平及相关因素。

方法

本研究采用横断面描述性设计,纳入 210 名诊断为急性心肌梗死的患者。参与者完成了一般药物依从量表(GMAS)、医院焦虑抑郁量表(HADS),并提供了社会人口统计学细节。

结果

研究显示 AMI 患者存在部分药物依从性,GMAS 得分为 33 分中的 24.89(±3.64)分。值得注意的是,由于患者行为(15 分中的平均±SD=11.8±2.3)和额外的疾病负担(12 分中的平均±SD=8.65±2.21)导致的非依从性中观察到良好的依从性,而由于经济限制导致的非依从性中观察到部分依从性(6 分中的平均±SD=4.44±1.34)。患者报告有轻度焦虑(平均±SD=8.38±2.81)和无抑郁症状(平均±SD=7.43±2.42)。多元线性回归分析表明,就业状况、年龄较小、MI 持续时间较短、焦虑和抑郁水平较低与更高的药物依从性相关。然而,月收入、性别、教育水平和婚姻状况等因素并不能预测药物依从性。

结论

本研究强调在设计干预措施以提高 AMI 患者药物依从性时,需要关注焦虑和抑郁水平,并考虑社会人口统计学因素。需要进一步研究以探索药物依从性的其他决定因素,并制定针对 AMI 后患者的个性化干预措施以改善患者结局。

相似文献

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Anxiety and depression after acute myocardial infarction.急性心肌梗死后的焦虑和抑郁
Heart Lung. 1996 Mar-Apr;25(2):98-107. doi: 10.1016/s0147-9563(96)80111-7.

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